Using micro-osteoperforations to speed up clear aligner treatment for crowded teeth

Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration of Dental Crowding Cases Treated With Clear Aligners: A Randomized Controlled Clinical Trial

Not applicable Interventional Hama University · NCT05492773

This study is testing if a new technique called micro-osteoperforations can help adults with crowded teeth get better results and feel more comfortable while using clear aligners.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years to 26 Years
SexAll
SponsorHama University Academic / other
Locations1 site (Hama)
Trial IDNCT05492773 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of the micro-osteoperforations technique in accelerating orthodontic tooth movement in patients with moderate mandibular anterior crowding undergoing treatment with clear aligners. Participants will be divided into two groups: one receiving traditional clear aligners with micro-osteoperforations and the other receiving clear aligners alone. The study will assess not only the speed of tooth movement but also patient pain levels and satisfaction throughout the treatment process. This approach aims to improve compliance and outcomes for adult patients who prefer less invasive orthodontic options.

Who should consider this trial

Good fit: Ideal candidates are adults with moderate anterior mandibular crowding who have completed their permanent dentition and are seeking orthodontic treatment with clear aligners.

Not a fit: Patients with systemic diseases affecting bone movement, those on medications that interfere with pain perception, or individuals with poor oral hygiene may not benefit from this study.

Why it matters

Potential benefit: If successful, this technique could significantly reduce treatment time for patients using clear aligners, leading to faster results and improved patient satisfaction.

How similar studies have performed: While the micro-osteoperforations technique is a relatively novel approach in orthodontics, similar methods have shown promise in accelerating tooth movement in other contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Completion of permanent dentition (except third molars)
* Moderate crowding (4-6 mm according to Little's index)
* Absence of medications intake that interferes with pain perception for at least one week before the beginning of the treatment
* Number of aligners ≥ 8 aligners.

Exclusion Criteria:

* • Systematic diseases that could affect bone and tooth movement and no contraindication avoid oral surgery

  * Medical conditions that affect tooth movement (Corticosteroid, NSAIDs)
  * Patients had previous orthodontic treatments
  * Poor oral hygiene or concurrent periodontal disease

Where this trial is running

Hama

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Crowding of Anterior Mandibular Teeth
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.