Using magnetic stimulation to help people with cannabis addiction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study explores the effectiveness of repetitive transcranial magnetic stimulation (rTMS) in reducing cravings, frequency of cannabis use, and the severity of cannabis use disorder (CUD) among participants. The research will compare different rTMS treatment schedules to determine their impact on these factors. Participants diagnosed with CUD will receive multiple rTMS sessions, and the study aims to assess the differences in outcomes based on the treatment schedule used.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Able to read and communicate in English and/or Chinese SToP-C-rTMS x CUD
* Able to give informed consent
* Using cannabis or marijuana as the primary psychoactive substance of abuse
* Diagnosed with Cannabis Use Disorder according to the Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5) by the Structured Clinical Interview for DSM-5 Disorders (SCID-5)

Exclusion Criteria:

* Age \<18 years old
* Unable to read English or Chinese
* Unable to give informed consent
* Had been diagnosed with the following disorders, including neurodevelopmental disorders, DSM-5 defined substance use disorder greater than moderate in severity, and neurocognitive disorders
* Contra-indicated to have rTMS, including subjects with electronic and/or magnetic implants (e.g. pacemaker, implantable cardioverter defibrillator \[ICD\], cerebral shunts, cochlear implant, etc.), with metallic or mechanic fragments (e.g., screws, plates, stents, clips, etc.), pregnant, with any known or history of neurological conditions including cerebral vascular accidents, epilepsy, brain tumor or space occupying lesion, poorly controlled or unstable diabetes mellitus, and receiving unstable dose(s) of antipsychotics, antidepressants, benzodiazepines and/or anticonvulsants in the past 6 months

Where it's running

• Queen Mary Hospital
  Hong Kong, Hong Kong Recruiting

Study contacts

• Principal investigator: Albert KK Chung, MBBS — Department of Psychiatry, The University of Hong Kong
• Study coordinator: Albert KK Chung, MBBS
• Email: Chungkka@hku.hk
• Phone: +85260440993

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Can tACS modulate motivation and reward signals in cannabis use disorder and depression

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  Recruiting Phase 2 Medical University of South Carolina · Charleston, South Carolina · NCT07815691

• Semaglutide for cannabis use disorder: see if a medicine helps reduce use

  This study tests whether weekly injections of semaglutide can help adults with cannabis use disorder reduce their cannabis use compared with placebo.

  Recruiting Phase 2 Psychiatric Centre Rigshospitalet · Frederiksberg · NCT07523633

• Brain imaging to predict teens' response to cannabis treatment

  This project will test whether teens' brain activity during a learning task can predict how well 14–17-year-olds do in a 10-week virtual reward program to reduce cannabis use.

  Recruiting Indiana University · Indianapolis, Indiana · NCT07340554

• Reducing cannabis use to improve daily functioning.

  This program will try an 8-week combination of motivational interviewing, computerized CBT (CBT4CBT), and small financial rewards to help adults with cannabis use disorder cut back on cannabis.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT07218471

• Home-based brain stimulation with guided mindfulness for cannabis use disorder

  This project tests whether daily at-home mild brain stimulation plus guided mindfulness can help adults with cannabis use disorder reduce or stop their cannabis use.

  Recruiting NYU Langone Health · New York, New York · NCT07184983

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.