Using lung tissues to study pulmonary fibrosis
Utilization of Explanted Lungs for Isolation of Tissue Samples and Primary Cell Lines to Study Pulmonary Fibrosis
This study looks at lung tissues from patients with pulmonary fibrosis to see what changes happen in the lungs and how it might help find new treatments for the disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 90 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT00515567 on ClinicalTrials.gov |
What this trial studies
This observational study aims to analyze explanted lung tissues from patients with pulmonary fibrosis to better understand the cellular mechanisms behind the disease. By comparing these tissues to those from patients without pulmonary fibrosis, researchers hope to identify the causes and progression of lung scarring. The study focuses on the cellular changes that occur in the lungs as they develop fibrosis, which impairs their ability to function properly. The findings could provide insights into potential therapeutic targets for treating this condition.
Who should consider this trial
Good fit: Ideal candidates for this study are patients awaiting lung transplants, particularly those diagnosed with pulmonary fibrosis.
Not a fit: Patients who do not provide consent or those not awaiting lung transplants will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and treatment options for patients suffering from pulmonary fibrosis.
How similar studies have performed: While this approach is focused on a specific aspect of pulmonary fibrosis, similar studies have shown promise in understanding lung diseases through tissue analysis.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * all patients awaiting lung transplant Exclusion Criteria: * all who will not give consent
Where this trial is running
Chicago, Illinois
- The University of Chicago — Chicago, Illinois, United States (Recruiting)
Study contacts
- Principal investigator: Nickolai Dulin, MD — University of Chicago
- Study coordinator: Nickolai Dulin, MD
- Email: ndulin@bsd.uchicago.edu
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.