Using lung tissues to study pulmonary fibrosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze explanted lung tissues from patients with pulmonary fibrosis to better understand the cellular mechanisms behind the disease. By comparing these tissues to those from patients without pulmonary fibrosis, researchers hope to identify the causes and progression of lung scarring. The study focuses on the cellular changes that occur in the lungs as they develop fibrosis, which impairs their ability to function properly. The findings could provide insights into potential therapeutic targets for treating this condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* all patients awaiting lung transplant

Exclusion Criteria:

* all who will not give consent

Where it's running

• The University of Chicago
  Chicago, Illinois, United States Recruiting

Study contacts

• Principal investigator: Nickolai Dulin, MD — University of Chicago
• Study coordinator: Nickolai Dulin, MD
• Email: ndulin@bsd.uchicago.edu

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Advanced imaging to see how immunosuppression affects lung fibrosis activity

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• 68Ga-NI-FAPI-04 PET/CT imaging to detect fibroblast activation in cancer, fibrotic, and heart diseases

  This test will see if an injected PET tracer called 68Ga-NI-FAPI-04 can better show fibroblast activation in people with tumors, pulmonary fibrosis, certain autoimmune vascular diseases, hypertrophic cardiomyopathy, or other cardiovascular conditions.

  Recruiting Phase 1/2 Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT07464132

• Home monitoring for patients with pulmonary fibrosis

  This study tests if using home monitoring and video calls can help people with pulmonary fibrosis manage their condition as well as or better than regular clinic visits.

  Recruiting at 11 sites Erasmus Medical Center · Amsterdam and 10 other locations · NCT06883448

• Understanding genetic and environmental factors in pulmonary fibrosis

  This study looks at how genes and environmental factors affect pulmonary fibrosis to help understand the disease better for people who have it.

  Recruiting Royal College of Surgeons, Ireland · Dublin · NCT06702228

• Identifying biomarkers for progressive pulmonary fibrosis in lung disease patients

  This study is trying to find early signs that can help predict if adults with certain lung diseases will develop progressive pulmonary fibrosis over the next five years.

  Recruiting Amsterdam UMC, location VUmc · Amsterdam, North Holland · NCT06644144

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.