Using Lemborexant to treat insomnia in patients with dementia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of lemborexant, a dual orexin receptor antagonist, in treating insomnia among patients with early-onset dementia. The study aims to address the challenges of using traditional sleeping aids, which can exacerbate cognitive impairment and other adverse effects in older adults. By focusing on a personalized approach, the trial evaluates how well lemborexant can improve sleep without the common side effects associated with conventional medications. Participants will receive a 5 MG dose of lemborexant to assess its impact on their insomnia symptoms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Identified by clinician investigator to have early-onset dementia and a significant component of insomnia.

Exclusion Criteria:

* Known sleep disorders that are contraindications for orexin antagonist therapy.

Where it's running

• Nova Scotia Health
  Halifax, Nova Scotia, Canada Recruiting

Study contacts

• Study coordinator: Shanna C Trenaman, BScPharm, PhD
• Email: shanna.trenaman@dal.ca
• Phone: 19024310559

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.