Using IVIG to treat gastrointestinal autoimmune neuropathy
Official title: IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy
Run by University of Louisville · NCT04208828 · Data updated 2026-11-12
This study is testing whether intravenous immunoglobulin (IVIG) can help people with autoimmune gastrointestinal issues feel better when other treatments haven't worked.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 12 Years to 90 Years |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | University of Louisville Academic / other |
| Locations | 1 site (Louisville, Kentucky) |
| Status | Recruiting |
| Started | January 2, 2020 |
| Main results expected | January 2, 2028 |
| Study ends | January 2, 2028 |
| Registry record updated | August 1, 2025 |
| Trial ID | NCT04208828 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with refractory gastrointestinal motor disorders who may have autoimmune components.
✕Probably not a fit
Patients who are unable to receive intravenous immunoglobulin will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on patients suffering from gastrointestinal motility disorders, particularly those with autoimmune findings who have not responded to standard treatments. It aims to document the clinical observations and responses of these patients to intravenous immunoglobulin (IVIG) therapy. Patients will complete standardized surveys to assess their gastrointestinal symptoms before and after receiving IVIG. The study seeks to identify the effectiveness of IVIG in managing symptoms of autoimmune gastrointestinal neuropathies.
Why it matters
Potential benefit: If successful, this study could provide a new treatment option for patients with refractory gastrointestinal motility disorders.
How similar studies have gone: Other studies have shown promising results with IVIG therapy in similar autoimmune conditions, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Patient with otherwise refractory symptoms of gastrointestinal (GI) motor disorders. \- Exclusion Criteria: Inability to receive intravenous immunoglobulin. \-
Where it's running
-
University of Louisville
Louisville, Kentucky, United States Recruiting
Study contacts
- Study coordinator: Thomas L Abell, MD
- Email: thomas.abell@louisville.edu
- Phone: (502)852-6991
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.