Clinical trial Recruiting at 1 site Observational Ages 12 to 90

Using IVIG to treat gastrointestinal autoimmune neuropathy

Official title: IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy

Run by University of Louisville · NCT04208828 · Data updated 2026-11-12

This study is testing whether intravenous immunoglobulin (IVIG) can help people with autoimmune gastrointestinal issues feel better when other treatments haven't worked.

Quick facts

Study typeObservational
Ages12 Years to 90 Years
SexAll
Enrollment400 (estimated)
SponsorUniversity of Louisville
Academic / other
Locations1 site (Louisville, Kentucky)
StatusRecruiting
StartedJanuary 2, 2020
Main results expectedJanuary 2, 2028
Study endsJanuary 2, 2028
Registry record updatedAugust 1, 2025
Trial IDNCT04208828 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with refractory gastrointestinal motor disorders who may have autoimmune components.

Probably not a fit

Patients who are unable to receive intravenous immunoglobulin will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients suffering from gastrointestinal motility disorders, particularly those with autoimmune findings who have not responded to standard treatments. It aims to document the clinical observations and responses of these patients to intravenous immunoglobulin (IVIG) therapy. Patients will complete standardized surveys to assess their gastrointestinal symptoms before and after receiving IVIG. The study seeks to identify the effectiveness of IVIG in managing symptoms of autoimmune gastrointestinal neuropathies.

Why it matters

Potential benefit: If successful, this study could provide a new treatment option for patients with refractory gastrointestinal motility disorders.

How similar studies have gone: Other studies have shown promising results with IVIG therapy in similar autoimmune conditions, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria: Patient with otherwise refractory symptoms of gastrointestinal (GI) motor disorders.

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Exclusion Criteria: Inability to receive intravenous immunoglobulin.

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Where it's running

  • University of Louisville
    Louisville, Kentucky, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.