Using intraoperative ventilation to predict postoperative air leaks after thoracoscopic lobectomy or segmentectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In the NODRAIN observational cohort, patients undergoing conventional or robotic thoracoscopic lobectomy or anatomical segmentectomy will receive a standardized intraoperative ventilation maneuver to detect air leaks at the end of the operation. Surgeons will still place routine chest drains and patients will receive standard postoperative care while intraoperative findings and postoperative air-leak duration are recorded. Investigators will analyze the correlation between intraoperative ventilation results and the occurrence or persistence of postoperative air leaks to identify a predictive threshold. Demonstrating a reliable threshold could allow some patients to avoid chest drains, reducing pain, length of stay, and costs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient with pulmonary lobectomy or Anatomical segmentectomy with closed chest (conventional or robotic thoracoscopy);
* Patient affiliated with a health insurance scheme.
* Person who has not objected to the collection of his/her data for the purpose of the study.

Exclusion Criteria:

* Patient undergoing any type of lung resection by thoracotomy;
* Patient with a history of thoracic surgery on the same side;
* Patient with pulmonary fibrosis;
* Patient from a vulnerable population as defined in Articles L.1121-5 to 8 of the French Public Health Code.
* Patient undergoing conversion to thoracotomy;
* Patient undergoing conversion from planned pulmonary lobectomy or anatomical segmentectomy to atypical resection, bilobectomy or pneumonectomy;
* Drainage via two chest drains;
* Absence of autonomous drainage system;
* Patient not extubated at the end of the procedure;
* Early reoperation, before drain removal, due to complications.

Where it's running

• Hôpital privé d'Anthony
  Antony, France Recruiting

Study contacts

• Principal investigator: Dr Madalina GRIGOROIU — Hôpital Privé d'Antony
• Study coordinator: Dr Madalina GRIGOROIU
• Email: madalina.grigoroiu@gmail.com
• Phone: (0)7 60 39 19 10

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Can short-term atorvastatin around surgery help prevent atrial fibrillation after lung surgery?

  This trial tests whether giving a short course of atorvastatin around surgery can reduce new atrial fibrillation after lung resection in adults aged 60 and older.

  Recruiting Phase 4 Peking Union Medical College Hospital · Beijing and 1 other locations · NCT07727681

• Right Ventricle Response After Major Lung Resection with Minimally Invasive or Open Surgery

  This study tests how the right side of the heart handles increased pressure after major lung surgery in patients with heart or lung risks, comparing minimally invasive procedures to open surgery.

  Recruiting Istituto Clinico Humanitas · Rozzano, MI · NCT07362342

• Evaluating neoadjuvant immunotherapy for lung cancer treatment outcomes

  This study is trying to see if giving immunotherapy before surgery helps people with non-small cell lung cancer live longer and feel better.

  Recruiting at 4 sites Peking University Cancer Hospital & Institute · Beijing, Beijing Municipality and 3 other locations · NCT06926179

• Gas analyzer for chest drains to detect pleural air leaks

  This study will test a small reusable gas analyzer that connects to chest drains to detect air leaks in adults undergoing thoracic surgery.

  Recruiting Lung Healing Technologies Inc · Evanston, Illinois · NCT06548386

• Using auricular acupressure to improve health before lung surgery

  This study is testing whether auricular acupressure can help improve the health and well-being of people aged 50 and older who are getting ready for major lung surgery.

  Recruiting University of Chicago · Chicago, Illinois · NCT06516198

• Early chest tube removal after lung surgery

  This study tests if taking out chest tubes on the same day after lung surgery can make recovery easier and more comfortable for patients.

  Recruiting London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT06444854

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.