Using inflatable air bags to improve lung function in ARDS patients in prone position

Improvement of Lung and Thoracic Compliance in ARDS Patients in Prone Position by Using Inflatable Air Bag

This study tests if using inflatable air bags can help improve lung function in patients with Acute Respiratory Distress Syndrome (ARDS) who are lying on their stomachs.

Quick facts

• Phase: PHASE2
• Study type: Interventional
• Enrollment: 30 (estimated)
• Ages: 18 Years and up
• Sex: All
• Sponsor: Centre Hospitalier Universitaire, Amiens (other)
• Locations: 1 site (Amiens)
• Trial ID: NCT05515484 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the use of inflatable air bags to enhance lung and thoracic compliance in patients with Acute Respiratory Distress Syndrome (ARDS) who are placed in a prone position. The study compares the effects of standard prone positioning with and without the use of air bags to alleviate pressure on the chest and abdomen, potentially reducing complications such as pressure ulcers. By focusing on patients under mechanical ventilation with a P/F ratio of less than 150, the trial aims to assess whether this innovative approach can improve patient outcomes in the intensive care setting.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old with ARDS under mechanical ventilation and a P/F ratio of less than 150.

Not a fit: Patients who are not eligible for prone positioning or those with a tracheostomy may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved lung function and reduced complications for ARDS patients in critical care.

How similar studies have performed: While the use of prone positioning in ARDS has been established, the specific application of inflatable air bags is a novel approach that has not been extensively tested in prior studies.

Eligibility criteria

Inclusion Criteria:

* patients with ARDS under mechanical ventilation with P/F ratio\<150
* Age \>18 y/o
* Admitted in the medical ICU of Amiens under mechanical ventilation sedated,
* With signed informed consent (patient or relative if patient is not conscious)

Exclusion Criteria:

* patients not eligible for a prone position
* Patients with tracheostomy

Where this trial is running

Amiens

• CHU Amiens — Amiens, France (RECRUITING)

Study contacts

• Study coordinator: Pr Michel Slama, Pr

Conditions: ARDS, Prone Position, Mechanical Ventilation, Airbag, prone position, mechanical ventilation, airbag