Using ICG dye to improve tumor margin identification during surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of indocyanine green (ICG) dye in identifying tumor margins during the surgical resection of benign and malignant bone or soft tissue masses. Patients will receive ICG via injection before surgery, and its fluorescence will be monitored during the procedure to ensure complete tumor removal. The study aims to determine if ICG-guided resection leads to better oncologic outcomes, including local recurrence and overall survival rates.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients 18 years of age or older who present to Massachusetts General Hospital Department of Orthopaedic Surgery with a benign or malignant bone or soft tissue mass that is consented for surgery during the study period.

Exclusion Criteria:

* Pregnant or nursing patients
* Patients with previously known anaphylaxis to IV contrast or iodine (other allergies may be considered on a case-by-case basis)
* Patients in renal failure who are not cleared for ICG administration by their primary physician or oncologist

Where it's running

• Massachusetts General Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Santiago A Lozano-Calderon, MD, PhD — Massachusetts General Hospital
• Study coordinator: Santiago A Lozano-Calderon, MD, PhD
• Email: SLOZANOCALDERON@mgh.harvard.edu
• Phone: (617) 643-4947

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.