Using Hyperbaric Oxygen Therapy for Recovery After Acute Ischemic Stroke
Hyperbaric Oxygen Therapy in Acute Ischemic Stroke Recovery
This study is testing if Hyperbaric Oxygen Therapy can help people recovering from a stroke improve their movement and daily activities while they are in rehab.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | LCMC Health Academic / other |
| Locations | 1 site (New Orleans, Louisiana) |
| Trial ID | NCT06148285 on ClinicalTrials.gov |
What this trial studies
This study investigates the feasibility, safety, and efficacy of Hyperbaric Oxygen Therapy (HBOT) during inpatient rehabilitation for patients recovering from acute ischemic stroke. It focuses on patients who are in the subacute phase of stroke, specifically those admitted to an inpatient rehab facility 7 to 30 days post-stroke. The study aims to assess the impact of HBOT on neurological outcomes, functional communication, activities of daily living, and mobility while minimizing risks associated with treatment. By providing daily one-hour HBOT sessions in a supervised setting, the study seeks to enhance recovery without disrupting the patients' rehabilitation plans.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who have experienced an ischemic stroke and are within 7 to 30 days post-event.
Not a fit: Patients with severe pre-stroke disabilities, recent seizures, or significant pulmonary issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve recovery outcomes for patients after an acute ischemic stroke.
How similar studies have performed: While preclinical studies suggest potential benefits of HBOT in stroke recovery, this specific application in the subacute phase is novel and has not been extensively tested in clinical settings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years and above * Ischemic stroke proven on neuroimaging * Within 7-30 days post-stroke on day 1 of treatment * Admitted to Touro Inpatient Rehab Facility Exclusion Criteria: * Pre-stroke modified Rankin Scale Score \>2 * Parenchymal hemorrhagic transformation (PH1 or PH2) * Receptive aphasia such that recommendations for preventative measures to mitigate barotrauma cannot be followed * History of recurrent and unprovoked seizures requiring a change in management in the last 3 months to control seizures * Pulmonary disease requiring supplemental oxygen or daily respiratory medication management (metered dose inhalers, nebulized treatment or steroids)
Where this trial is running
New Orleans, Louisiana
- Touro Infirmary New Orleans — New Orleans, Louisiana, United States (Recruiting)
Study contacts
- Study coordinator: Lawrence Matarutse
- Email: Lawrence.Matarutse@lcmchealth.org
- Phone: 504-962-6419
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.