Using Hyperbaric Oxygen Therapy for Recovery After Acute Ischemic Stroke
Official title: Hyperbaric Oxygen Therapy in Acute Ischemic Stroke Recovery
Run by LCMC Health · NCT06148285 · Data updated 2026-11-12
This study is testing if Hyperbaric Oxygen Therapy can help people recovering from a stroke improve their movement and daily activities while they are in rehab.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | LCMC Health Academic / other |
| Locations | 1 site (New Orleans, Louisiana) |
| Status | Recruiting |
| Started | May 24, 2022 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | November 28, 2023 |
| Trial ID | NCT06148285 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who have experienced an ischemic stroke and are within 7 to 30 days post-event.
✕Probably not a fit
Patients with severe pre-stroke disabilities, recent seizures, or significant pulmonary issues may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the feasibility, safety, and efficacy of Hyperbaric Oxygen Therapy (HBOT) during inpatient rehabilitation for patients recovering from acute ischemic stroke. It focuses on patients who are in the subacute phase of stroke, specifically those admitted to an inpatient rehab facility 7 to 30 days post-stroke. The study aims to assess the impact of HBOT on neurological outcomes, functional communication, activities of daily living, and mobility while minimizing risks associated with treatment. By providing daily one-hour HBOT sessions in a supervised setting, the study seeks to enhance recovery without disrupting the patients' rehabilitation plans.
Why it matters
Potential benefit: If successful, this approach could significantly improve recovery outcomes for patients after an acute ischemic stroke.
How similar studies have gone: While preclinical studies suggest potential benefits of HBOT in stroke recovery, this specific application in the subacute phase is novel and has not been extensively tested in clinical settings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years and above * Ischemic stroke proven on neuroimaging * Within 7-30 days post-stroke on day 1 of treatment * Admitted to Touro Inpatient Rehab Facility Exclusion Criteria: * Pre-stroke modified Rankin Scale Score \>2 * Parenchymal hemorrhagic transformation (PH1 or PH2) * Receptive aphasia such that recommendations for preventative measures to mitigate barotrauma cannot be followed * History of recurrent and unprovoked seizures requiring a change in management in the last 3 months to control seizures * Pulmonary disease requiring supplemental oxygen or daily respiratory medication management (metered dose inhalers, nebulized treatment or steroids)
Where it's running
-
Touro Infirmary New Orleans
New Orleans, Louisiana, United States Recruiting
Study contacts
- Study coordinator: Lawrence Matarutse
- Email: Lawrence.Matarutse@lcmchealth.org
- Phone: 504-962-6419
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Short-Term outside-in nerve stimulation for acute ischemic stroke
This trial tests whether a 5-day external trigeminal nerve stimulation given after stroke can help more patients recover better than a sham treatment.
-
Sevoflurane vs. Propofol for anesthesia in stroke patients undergoing clot-removal
This study tests whether sevoflurane or propofol used for anesthesia during endovascular treatment of an acute ischemic stroke affects the final brain damage and recovery.
-
Safety of adding NRICM301 to standard care for adults with acute ischemic stroke
This study tests whether adding NRICM301, a traditional Chinese medicine formula, to usual care is safe for adults with acute ischemic stroke.
-
Intracranial Recanalization with LT3001 in Acute Ischemic Stroke
This phase II study tests whether LT3001 given to adults with acute ischemic stroke can help reopen blocked brain arteries.
-
Mobilisation After Endovascular Stroke Treatment
This study checks whether moving around 12 hours after endovascular stroke treatment is as safe as moving around 24 hours for people with an acute ischemic stroke.
-
Endovascular therapy plus standard care vs standard care alone for distal and medium vessel strokes
In people with acute ischemic stroke due to distal or medium vessel blockages, this study tests whether adding endovascular treatment to the usual medical care helps improve outcomes compared with medical care alone.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.