Using Gen 6 high-sensitivity Troponin T to rule out heart attack faster

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares the sixth-generation high-sensitivity cardiac troponin T assay with the fifth-generation assay in patients with suspected acute coronary syndrome. The goal is to see if the Gen 6 test shortens time to diagnosis and supports safer, earlier discharge decisions. Data will be drawn from routine clinical care within participating Scottish hospitals to evaluate workflow and patient outcomes. No randomized design is described; it appears to use a before-and-after approach to implement the Gen 6 assay across the health board. The study is led by the University of Edinburgh with Roche Diagnostics as a collaborator.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years and over.
* Attending clinician suspects acute coronary syndrome.
* At least one measurement of cardiac troponin using the Gen 5 or Gen 6 hs-cTnT assay.

Exclusion Criteria:

* Insufficient clinical information to perform record linkage.
* Not resident in Scotland.
* Previous enrolment in the study.

Where it's running

• The Royal Infirmary of Edinburgh
  Edinburgh, Midlothian, United Kingdom Recruiting
• Western General Hospital
  Edinburgh, Midlothian, United Kingdom Recruiting
• St. John's Hospital
  Livingston, West Lothian, United Kingdom Recruiting

Study contacts

• Principal investigator: Andrew R Chapman, MD PhD — University of Edinburgh
• Study coordinator: Andrew R Chapman, MD PhD
• Email: a.r.chapman@ed.ac.uk
• Phone: +44131 242 6200

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.