Using electrical stimulation to treat bedwetting in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial involves children aged 5-17 who are experiencing primary nocturnal enuresis and have not responded to behavioral modifications. Participants will be randomized into two groups to receive transcutaneous electrical nerve stimulation (TENS) with different pulse widths: one group at 260 microseconds and the other at 50 microseconds. The TENS unit will be applied nightly for 30 minutes over a period of 30 days, with caregivers instructed on its use. The effectiveness of the treatment will be monitored through diaries documenting nighttime incontinence.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Presenting with nocturnal enuresis (more than 1x a week)
2. Failed Behavioral modification treatment (limiting evening drinking, double voiding prior to bedtime, bowel habits, social anxiety factors) during the 30 day period prior to randomization
3. Ability to provide informed consent and assent and complete study requirements

Exclusion Criteria:

1. Patients who have previously tried pharmacologic treatment for nocturnal enuresis, neuromodulation or other alternative therapy for urologic disorders within the past 30 days
2. Daytime incontinence symptoms
3. Known "high volume" voiders (determined from history)
4. Bedwetting episodes on the average of less than two times per week,
5. Medications predisposing to incontinence (eg, Lithium for bipolar disorder)
6. Other known voiding or neurologic disorders (eg, overactive bladder, myelomeningocele, interstitial cystitis, etc)
7. Secondary etiologies for nocturnal enuresis (eg, cystitis, obstructive sleep apnea, urinary fistulae, heart disease)
8. Any contraindications to usage of a TENS unit (pacemaker or other implantable device, lymphedema, pregnancy, malignancy, bleeding or clotting disorders, unhealthy tissue, seizure disorders, impaired cognition)
9. Any history of heart disease or complications

Where it's running

• Albany Medical College
  Albany, New York, United States Recruiting

Study contacts

• Principal investigator: Adam Howe, MD — Albany Medical College
• Study coordinator: Brenda Romeo, CCRC
• Email: romeob@amc.edu
• Phone: 518-262-3349

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Single-Lumen Midline Catheter vs Ultrasound-Guided Peripheral IV by ED Nurses

  This study tests whether a ultrasound-guided single-lumen midline catheter works better than an ultrasound-guided long peripheral IV for ED patients with difficult IV access, when inserted by bedside nurses.

  Recruiting Albany Medical College · Albany, New York · NCT07779317

• Thoracentesis to remove lung fluid for adults hospitalized with worsening heart failure and pleural effusion

  This study will test whether removing fluid around the lungs with thoracentesis plus usual heart-failure treatment helps reduce shortness of breath in adults hospitalized with acute decompensated heart failure and moderate-to-large pleural effusions.

  Recruiting Albany Medical College · Albany, New York · NCT07419360

• Using patient-chosen visual art to improve hospital satisfaction during pregnancy admissions

  This study tests if letting pregnant patients choose the artwork in their hospital room can make them feel happier and more satisfied during their stay.

  Recruiting Albany Medical College · Albany, New York · NCT06790043

• Using vibrators to enhance sexual and pelvic floor function in women with urogynecological issues

  This study is testing if using vibrators can help women with urogynecological issues improve their sexual and pelvic floor function.

  Recruiting Albany Medical College · Albany, New York · NCT06677541

• Software fusion versus cognitive (visual) MRI-guided ultrasound biopsy for prostate cancer detection

  This study will test whether MRI-targeted biopsy using software fusion or cognitive (visual) fusion finds more clinically significant prostate cancer in men with suspicious mp‑MRI lesions.

  Recruiting at 2 sites Albany Medical College · Burlington, Massachusetts and 3 other locations · NCT06517901

• Using anti-inflammatory drugs to lower PSA levels in men

  This study is testing if taking ibuprofen can lower PSA levels in men with high readings to help avoid unnecessary prostate biopsies.

  Recruiting at 3 sites Phase 4 Albany Medical College · Chicago, Illinois and 2 other locations · NCT05629494

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.