Using Diosmin and Hesperidin to Treat Rheumatoid Arthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of a combination of flavonoids, diosmin and hesperidin, as an adjuvant therapy for patients with rheumatoid arthritis. It focuses on assessing the anti-inflammatory and antioxidant properties of these compounds, alongside clinical and functional evaluations of disease activity. Additionally, the study aims to investigate the hepatoprotective effects of the treatment against liver adverse events caused by methotrexate, a common medication for rheumatoid arthritis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with mild to moderate disease activity.
* Patient age must be more than 18 years.

Exclusion Criteria:

* Pregnant and lactating females.
* Patients with liver, renal impairment or any other inflammatory diseases.
* Patients on TNF-α (tumor necrosis factor- α) or IL-1β (interleukin-1β) antagonists.

Where it's running

• Alexandria university hospital
  Alexandria, Egypt Recruiting

Study contacts

• Principal investigator: AHMED ABDELBAR, MSc — College of Pharmacy - Arab Academy for Science and Technology
• Study coordinator: AHMED ABDELBAR, MSc
• Email: dr.ahmed_post@yahoo.com
• Phone: 00201021914588

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.