Using different volumes of PENG block for pain relief after hip replacement surgery

Comparison of the Impacts of Ultrasound-guided Pericapsular Nerve Group (PENG) Block Applied in Different Volumes on Postoperative Pain in Hip Replacement Surgeries: A Randomized Clinical Trial

Not applicable Interventional Istanbul Medeniyet University · NCT06166602

This study is testing different amounts of a pain relief injection for people having hip replacement surgery to see which one helps them feel better after the operation.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorIstanbul Medeniyet University Academic / other
Locations1 site (Istanbul)
Trial IDNCT06166602 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of the Pericapsular Nerve Group (PENG) block, a regional anesthesia technique, in managing postoperative pain for patients undergoing hip replacement surgery. By administering varying volumes of local anesthetic, the study aims to determine the optimal dosage for pain relief. Patients will be randomly assigned to receive either of the two volumes of the PENG block after obtaining informed consent. The study will monitor pain levels and recovery outcomes to assess the effectiveness of the different volumes used.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18-80 scheduled for hip replacement surgery who can provide informed consent.

Not a fit: Patients with coagulopathy, local anesthetic allergies, advanced organ failure, or those who are pregnant will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing hip replacement surgery.

How similar studies have performed: While the PENG block has shown promise in previous studies, this specific investigation into varying volumes is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients with informed consent
2. Patients planned for hip surgery
3. Those between the ages of 18-80
4. ASA (American Society of Anesthesiologists) I-III patients

Exclusion Criteria:

1. Patients who do not give consent
2. Patients with coagulopathy
3. Patients with a history of local anesthetic drug allergy and toxicity
4. Patients with advanced organ failure
5. Patients with mental retardation
6. Patients with infection at the injection site
7. Pediatric patients and patients over 80 years of age
8. Pregnant patients will not be included in the study.

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Regional AnesthesiaPostoperative PainHip Surgery
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.