Using diaphragm ultrasound to predict respiratory complications after surgery
Official title: Diaphragm Dysfunction and Respiratory Complications in the Perioperative Setting- Can Diaphragm Ultrasound Aid Prediction?
Run by Karolinska University Hospital · NCT05906030 · Data updated 2026-11-12
This study is testing if using ultrasound to check diaphragm function can help predict breathing problems after major surgeries.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 160 (estimated) |
| Sponsor | Karolinska University Hospital Academic / other |
| Drugs / interventions | radiation |
| Locations | 2 sites (Stockholm, Stockholm County and 1 other locations) |
| Status | Recruiting |
| Started | September 1, 2024 |
| Main results expected | September 1, 2026 |
| Study ends | September 1, 2027 |
| Registry record updated | January 29, 2025 |
| Trial ID | NCT05906030 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults scheduled for major elective abdominal, pelvic, or vascular surgery.
✕Probably not a fit
Patients under 18 years old or those with chronic respiratory diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the relationship between diaphragm function, as measured by ultrasound, and the occurrence of respiratory complications in patients undergoing major elective abdominal, pelvic, or vascular surgery. Diaphragm ultrasound will be performed both preoperatively and postoperatively to assess diaphragm thickening fraction, excursion, and density. The study will collect various physiological and laboratory parameters, along with data on surgery, anesthesia, and comorbidities, to correlate these with postoperative respiratory events such as pneumonia and desaturation. The goal is to identify predictive markers that could help mitigate complications following surgery.
Why it matters
Potential benefit: If successful, this study could lead to improved prediction and prevention of respiratory complications in postoperative patients.
How similar studies have gone: While the approach of using diaphragm ultrasound in the perioperative setting is relatively novel, similar studies have shown promising results in predicting respiratory complications in other contexts.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Adults undergoing elective (study 1) or acute (study 2) abdominal, pelvic or vascular surgery Exclusion Criteria: * \<18 years * Underlying chronic respiratory disease * Patients not able to give informed consent
Where it's running
-
Karolinska University Hospital, Perioperative Medicine and Intensive Care
Stockholm, Stockholm County, Sweden Recruiting -
Karolinska University Hospital
Stockholm, Sweden Recruiting
Study contacts
- Principal investigator: Jessica Kåhlin — Karolinska Universitetssjukhuset Solna
- Study coordinator: Jessica Kåhlin, MD, PhD
- Email: jessica.kahlin@regionstockholm.se
- Phone: 0707295456
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.