Using Dexmedetomidine for Pain Relief in Non-intubated Lung Surgery
Adjunctive Dexmedetomidine Infusion in Non-intubated Video-assisted Thoracoscopic Surgery
PHASE4 · Tri-Service General Hospital · NCT05863416
This study is testing if using dexmedetomidine can help relieve pain and improve recovery for patients having lung surgery without being intubated.
Quick facts
| Phase | PHASE4 |
|---|---|
| Study type | Interventional |
| Enrollment | 144 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Tri-Service General Hospital (other) |
| Locations | 1 site (Taipei) |
| Trial ID | NCT05863416 on ClinicalTrials.gov |
What this trial studies
This prospective study evaluates the effectiveness of dexmedetomidine (DEX) for postoperative analgesia and recovery in patients undergoing non-intubated video-assisted thoracoscopic surgery (VATS). The study aims to minimize the adverse effects associated with tracheal intubation and general anesthesia by using DEX, which has sedative and analgesic properties. Researchers will also assess the impact of DEX on anesthetic requirements, hemodynamic parameters, and any adverse events during the procedure. The goal is to improve clinical outcomes and reduce postoperative complications.
Who should consider this trial
Good fit: Ideal candidates include patients aged 18 to 80 with an ASA score of I-III who are scheduled for video-assisted thoracoscopic surgery.
Not a fit: Patients who may not benefit include those under 18 or over 80 years old, those with ASA classifications greater than III, pregnant individuals, and those with known allergies to study drugs.
Why it matters
Potential benefit: If successful, this approach could lead to improved pain management and recovery for patients undergoing lung surgery without the need for intubation.
How similar studies have performed: Other studies have shown promising results using dexmedetomidine for similar applications, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * American Society of Anesthesiologists (ASA) score of I-III patients receiving video-assisted thoracoscopic surgery Exclusion Criteria: * Age \< 18 or \> 80 years * ASA classifications \> III * Pregnancy * Known allergies to any drugs used in the study * Emergency surgery * Patient refusal * Chronic pain history
Where this trial is running
Taipei
- Tri-Service General Hospital — Taipei, Taiwan (RECRUITING)
Study contacts
- Study coordinator: Wei-Cheng Tseng, MD
- Email: ndmc_wechern@yahoo.com.tw
- Phone: 886-2-8792-3311
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Dexmedetomidine, Thoracoscopy, Analgesia