Clinical trial Recruiting at 1 site Interventional Ages 18 to 40 Women only

Using dexmedetomidine for pain relief after cesarean sections

Official title: Wound Infiltration With Dexmedetomidine in Cesarean Section: Effect on Postoperative Analgesia

Run by Attikon Hospital · NCT03382938 · Data updated 2026-11-12

This study is testing if using dexmedetomidine for pain relief after cesarean sections works better than other options for women recovering from surgery.

Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexWomen only
Enrollment100 (estimated)
SponsorAttikon Hospital
Academic / other
Locations1 site (Athens, Other)
StatusRecruiting
StartedAugust 23, 2019
Main results expectedDecember 20, 2025
Study endsNovember 20, 2026
Registry record updatedMarch 19, 2025
Trial IDNCT03382938 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are pregnant women over 37 weeks, classified as ASA I-II, with a BMI of 35 or less.

Probably not a fit

Patients with severe systemic diseases, high-risk pregnancies, or contraindications to epidural techniques may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of four different wound infiltration protocols on postoperative pain management in women undergoing cesarean sections. Participants will be randomly assigned to receive either dexmedetomidine, ropivacaine, a combination of both, or a placebo saline solution for pain relief at the surgical site. The study will measure pain intensity, morphine consumption, side effects, and overall satisfaction of the parturients. The goal is to determine the most effective method for reducing postoperative pain in this population.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for women after cesarean sections.

How similar studies have gone: Other studies have shown promising results with similar approaches to pain management in postoperative settings, suggesting potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* pregnancy \>37 weeks, ASA I-II, BMI\<35

Exclusion Criteria:

* patient refusal, epilepsy, GERD, morbid obesity, drug allergy, ASA class \>2, presence of atrioventricular block, severe systemic disease, multiple gestation, high risk pregnancy, contraindications to epidural technique, a history of severe systemic disease, recreational drug or alcohol use

Where it's running

  • Paraskevi K Matsota
    Athens, Other, Greece
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.