Using dexmedetomidine for pain relief after cesarean sections
Wound Infiltration With Dexmedetomidine in Cesarean Section: Effect on Postoperative Analgesia
This study is testing if using dexmedetomidine for pain relief after cesarean sections works better than other options for women recovering from surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | Female |
| Sponsor | Attikon Hospital Academic / other |
| Locations | 1 site (Athens, Other) |
| Trial ID | NCT03382938 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of four different wound infiltration protocols on postoperative pain management in women undergoing cesarean sections. Participants will be randomly assigned to receive either dexmedetomidine, ropivacaine, a combination of both, or a placebo saline solution for pain relief at the surgical site. The study will measure pain intensity, morphine consumption, side effects, and overall satisfaction of the parturients. The goal is to determine the most effective method for reducing postoperative pain in this population.
Who should consider this trial
Good fit: Ideal candidates are pregnant women over 37 weeks, classified as ASA I-II, with a BMI of 35 or less.
Not a fit: Patients with severe systemic diseases, high-risk pregnancies, or contraindications to epidural techniques may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for women after cesarean sections.
How similar studies have performed: Other studies have shown promising results with similar approaches to pain management in postoperative settings, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * pregnancy \>37 weeks, ASA I-II, BMI\<35 Exclusion Criteria: * patient refusal, epilepsy, GERD, morbid obesity, drug allergy, ASA class \>2, presence of atrioventricular block, severe systemic disease, multiple gestation, high risk pregnancy, contraindications to epidural technique, a history of severe systemic disease, recreational drug or alcohol use
Where this trial is running
Athens, Other
- Paraskevi K Matsota — Athens, Other, Greece (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.