Using dexmedetomidine for pain relief after cesarean sections
Official title: Wound Infiltration With Dexmedetomidine in Cesarean Section: Effect on Postoperative Analgesia
Run by Attikon Hospital · NCT03382938 · Data updated 2026-11-12
This study is testing if using dexmedetomidine for pain relief after cesarean sections works better than other options for women recovering from surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | Women only |
| Enrollment | 100 (estimated) |
| Sponsor | Attikon Hospital Academic / other |
| Locations | 1 site (Athens, Other) |
| Status | Recruiting |
| Started | August 23, 2019 |
| Main results expected | December 20, 2025 |
| Study ends | November 20, 2026 |
| Registry record updated | March 19, 2025 |
| Trial ID | NCT03382938 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are pregnant women over 37 weeks, classified as ASA I-II, with a BMI of 35 or less.
✕Probably not a fit
Patients with severe systemic diseases, high-risk pregnancies, or contraindications to epidural techniques may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of four different wound infiltration protocols on postoperative pain management in women undergoing cesarean sections. Participants will be randomly assigned to receive either dexmedetomidine, ropivacaine, a combination of both, or a placebo saline solution for pain relief at the surgical site. The study will measure pain intensity, morphine consumption, side effects, and overall satisfaction of the parturients. The goal is to determine the most effective method for reducing postoperative pain in this population.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for women after cesarean sections.
How similar studies have gone: Other studies have shown promising results with similar approaches to pain management in postoperative settings, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * pregnancy \>37 weeks, ASA I-II, BMI\<35 Exclusion Criteria: * patient refusal, epilepsy, GERD, morbid obesity, drug allergy, ASA class \>2, presence of atrioventricular block, severe systemic disease, multiple gestation, high risk pregnancy, contraindications to epidural technique, a history of severe systemic disease, recreational drug or alcohol use
Where it's running
-
Paraskevi K Matsota
Athens, Other, Greece Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.