Using Dexamethasone to improve pain management in hip surgery

Efficacy of Perineural Dexamethasone to Prolong Anesthesia After Erector Spinae Plane Block for Total Hip Arthroplasty

PHASE4 · Poznan University of Medical Sciences · NCT06789042

This study is testing if adding Dexamethasone to a pain relief method can help older patients have less pain and need fewer opioids after hip surgery.

Quick facts

PhasePHASE4
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorPoznan University of Medical Sciences (other)
Locations1 site (Poznan, Wielkopolska)
Trial IDNCT06789042 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of adding Dexamethasone to the Erector Spinae Plane Block for patients undergoing total hip arthroplasty. The goal is to reduce postoperative pain and inflammation, thereby minimizing opioid use and its associated side effects. The study involves administering either a saline solution or Dexamethasone to patients aged 65 to 100 years who are scheduled for hip surgery. Participants will be monitored for pain levels and recovery outcomes following the procedure.

Who should consider this trial

Good fit: Ideal candidates are patients aged over 65 years who are scheduled for total hip arthroplasty and can provide informed consent.

Not a fit: Patients with cognitive impairments or language barriers that prevent informed consent may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly enhance pain management and recovery for patients undergoing hip surgery.

How similar studies have performed: Other studies have shown promising results with similar regional anesthesia techniques, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients scheduled for total hip arthroplasty
* patients aged \>65 and \<100 years
* patients able to provide informed consent
* patients able to reliably report symptoms to the research team

Exclusion Criteria:

* inability to provide first-party consent due to cognitive impairment or a language barrier

Where this trial is running

Poznan, Wielkopolska

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Hip Osteoarthritis, Hip Arthropathy, Hip Arthritis, erector spinae plane block, total hip arthroplasty, pain management, perineural adjuvant

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.