Using continuous glucose monitoring for newborns with brain injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of continuous glucose monitoring (CGM) in managing glucose levels in neonates diagnosed with moderate to severe hypoxic ischemic encephalopathy (HIE) following perinatal asphyxia. Neonates will be randomly assigned to receive either CGM or standard care within six hours of birth, and their glucose levels will be monitored for 72 hours. The primary goal is to determine if CGM can increase the time spent within target glucose concentrations, thereby improving outcomes related to glucose variability and preventing extreme glucose levels.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Birth weight \>1.8kg
* Gestation \>35 weeks
* Aged \<6hours
* Moderate or severe HIE following perinatal asphyxia

Exclusion Criteria:

* Major congenital malformations
* Inborn errors of metabolism,
* Congenital infections
* Imminent death

Where it's running

• University of Campania Luigi Vanvitelli
  Naples, Italy Recruiting
• A.O.S.G. Moscati
  Avellino, Italy Not yet recruiting
• Monaldi | | AORN - Ospedali dei ColliAORN - Ospedali dei Colli
  Naples, Italy Not yet recruiting

Study contacts

• Study coordinator: Paolo Montaldo, PhD
• Email: paolo.montaldo@unicampania.it
• Phone: 0815664023

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.