Using blood tests to improve follow-up care for anal cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates whether circulating tumor DNA (ctDNA) can enhance the detection of early treatment failures or recurrences in patients with localized squamous cell carcinoma of the anus (SCCA) after receiving curative chemoradiotherapy. By comparing standard follow-up programs with ctDNA-guided imaging follow-up, the study aims to improve patient outcomes and increase the chances of curative surgery. Additionally, it seeks to establish early interventions to manage late morbidities associated with the disease.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with SCCA eligible for definitive (chemo)radiotherapy
* ≥ 18 of years
* Written and oral consent

Exclusion Criteria:

* Conditions that will contraindicate blood samples
* Conditions that will contraindicate a PET-CT scan.
* Potential lack of compliance to standard FU program and study participation.

Where it's running

• Department of Oncology Herlev and Gentofte Hospital
  Herlev, Capital Region of Denmark, Denmark Recruiting
• Department of Oncology, Vejle Hospital
  Vejle, The Regions of Southern Denmark, Denmark Recruiting
• Aarhus University Hospital
  Aarhus, Denmark Recruiting
• Tampere University Hospital
  Tampere, Finland Not yet recruiting
• Turku University Hospital
  Turku, Finland Not yet recruiting
• Haukeland University Hospital
  Bergen, Norway Not yet recruiting

Study contacts

• Principal investigator: Karen-Lise G Spindler, Professor — Department of Experimental Clinical Oncology Aarhus Univeristy Hospital
• Study coordinator: Karen-Lise G Spindler, Professor
• Email: k.g.spindler@rm.dk
• Phone: 91137244

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.