Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using blood tests to analyze tumor DNA in breast and digestive cancers

Official title: Interest of Circulating Tumor DNA in Digestive and Gynecologic/Breast Cancer

Run by Poitiers University Hospital · NCT04530890 · Data updated 2026-11-12

This study is testing whether blood tests that look for tumor DNA can help improve treatment and monitoring for people with breast, digestive, and gynecologic cancers.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorPoitiers University Hospital
Academic / other
Drugs / interventionschemotherapy, immunotherapy
Locations1 site (Poitiers)
StatusRecruiting
StartedMarch 8, 2021
Main results expectedMarch 2032
Study endsMarch 2032
Registry record updatedDecember 24, 2025
Trial IDNCT04530890 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults with proven or suspected digestive or gynecological/breast cancer who require oncological treatment.

Probably not a fit

Patients with a history of other cancers within the past five years may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of circulating tumor DNA (ctDNA) obtained from blood samples to improve the management of patients with breast, digestive, and gynecologic cancers. By employing advanced molecular biology techniques like Next Generation Sequencing (NGS), the study aims to assess the diagnostic, prognostic, and predictive capabilities of ctDNA in response to oncological treatments. Additionally, the study explores the potential of exosomes as future biomarkers in cancer management. The research focuses on patients requiring chemotherapy or immunotherapy, providing a non-invasive method to monitor tumor characteristics.

Why it matters

Potential benefit: If successful, this approach could lead to more personalized and effective treatment strategies for cancer patients.

How similar studies have gone: Other studies have shown promise in using ctDNA for cancer management, indicating a growing interest and potential in this area.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Digestive or gynecological / breast cancer proven or suspected, requiring oncological treatment (chemotherapy or immunotherapy)
* Major patient
* Patients benefiting from a Social Security scheme or benefiting through the intermediary of a third party
* Information note and collection of non-opposition after clear and fair information about the study

Exclusion Criteria:

* Linguistic or psychological refusal or inability to understand and / or sign the information and no-objection note
* History of a cancer other than that allowing inclusion in the 5 years preceding inclusion

Where it's running

  • CHU POitiers
    Poitiers, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.