Using blood tests to analyze tumor DNA in breast and digestive cancers
Official title: Interest of Circulating Tumor DNA in Digestive and Gynecologic/Breast Cancer
Run by Poitiers University Hospital · NCT04530890 · Data updated 2026-11-12
This study is testing whether blood tests that look for tumor DNA can help improve treatment and monitoring for people with breast, digestive, and gynecologic cancers.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Poitiers University Hospital Academic / other |
| Drugs / interventions | chemotherapy, immunotherapy |
| Locations | 1 site (Poitiers) |
| Status | Recruiting |
| Started | March 8, 2021 |
| Main results expected | March 2032 |
| Study ends | March 2032 |
| Registry record updated | December 24, 2025 |
| Trial ID | NCT04530890 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults with proven or suspected digestive or gynecological/breast cancer who require oncological treatment.
✕Probably not a fit
Patients with a history of other cancers within the past five years may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the use of circulating tumor DNA (ctDNA) obtained from blood samples to improve the management of patients with breast, digestive, and gynecologic cancers. By employing advanced molecular biology techniques like Next Generation Sequencing (NGS), the study aims to assess the diagnostic, prognostic, and predictive capabilities of ctDNA in response to oncological treatments. Additionally, the study explores the potential of exosomes as future biomarkers in cancer management. The research focuses on patients requiring chemotherapy or immunotherapy, providing a non-invasive method to monitor tumor characteristics.
Why it matters
Potential benefit: If successful, this approach could lead to more personalized and effective treatment strategies for cancer patients.
How similar studies have gone: Other studies have shown promise in using ctDNA for cancer management, indicating a growing interest and potential in this area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Digestive or gynecological / breast cancer proven or suspected, requiring oncological treatment (chemotherapy or immunotherapy) * Major patient * Patients benefiting from a Social Security scheme or benefiting through the intermediary of a third party * Information note and collection of non-opposition after clear and fair information about the study Exclusion Criteria: * Linguistic or psychological refusal or inability to understand and / or sign the information and no-objection note * History of a cancer other than that allowing inclusion in the 5 years preceding inclusion
Where it's running
-
CHU POitiers
Poitiers, France Recruiting
Study contacts
- Study coordinator: Camille EVRARD, PHD
- Email: camille.evrard@chu-poitiers.fr
- Phone: +33549444279
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.