Clinical trial Recruiting at 2 sites Observational Ages 18 and up

Using artificial intelligence to enhance endobronchial ultrasound for lung cancer evaluation

Official title: Automatic Segmentation of Mediastinal Lymph Nodes and Blood Vessels in Endobronchial Ultrasound (EBUS) Images Using a Deep Neural Network

Run by Norwegian University of Science and Technology · NCT05739331 · Data updated 2026-11-12

This study is testing if using artificial intelligence can help doctors better identify important lymph nodes during lung cancer ultrasound exams.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorNorwegian University of Science and Technology
Academic / other
Locations2 sites (Levanger and 1 other locations)
StatusRecruiting
StartedMay 1, 2023
Main results expectedMay 1, 2027
Study endsDecember 1, 2027
Registry record updatedSeptember 30, 2026
Trial IDNCT05739331 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older who have undiagnosed enlarged mediastinal and hilar lymph nodes.

Probably not a fit

Patients who are pregnant or deemed inappropriate for the study by the investigator will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of a deep neural network (DNN) in identifying mediastinal and hilar lymph nodes during endobronchial ultrasound (EBUS) procedures. It is a multi-center prospective feasibility study that trains the DNN on annotated ultrasound images to improve the segmentation of lymph nodes and blood vessels. The study consists of two parts: the first assesses the DNN's performance on static EBUS images, while the second evaluates its real-time application during EBUS procedures.

Why it matters

Potential benefit: If successful, this approach could lead to more accurate and efficient evaluations of lung cancer, improving patient outcomes.

How similar studies have gone: While the use of artificial intelligence in medical imaging is a growing field, this specific application in EBUS is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects referred to thoracic department in any of the participating hospitals with undiagnosed enlarged mediastinal and hilar lymph nodes.
* Subjects have to be ≥ 18 years of age

Exclusion Criteria:

* Pregnancy
* Any patient that the Investigator feels is not appropriate for this study for any reason.

Where it's running

  • Department of Pulmonology, Levanger Hospital, North Trøndelag Hospital Trust
    Levanger, Norway
    Recruiting
  • Department of Thoracic Medicine, St Olavs Hospital
    Trondheim, Norway
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.