Using artificial intelligence to enhance endobronchial ultrasound for lung cancer evaluation
Official title: Automatic Segmentation of Mediastinal Lymph Nodes and Blood Vessels in Endobronchial Ultrasound (EBUS) Images Using a Deep Neural Network
Run by Norwegian University of Science and Technology · NCT05739331 · Data updated 2026-11-12
This study is testing if using artificial intelligence can help doctors better identify important lymph nodes during lung cancer ultrasound exams.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Norwegian University of Science and Technology Academic / other |
| Locations | 2 sites (Levanger and 1 other locations) |
| Status | Recruiting |
| Started | May 1, 2023 |
| Main results expected | May 1, 2027 |
| Study ends | December 1, 2027 |
| Registry record updated | September 30, 2026 |
| Trial ID | NCT05739331 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older who have undiagnosed enlarged mediastinal and hilar lymph nodes.
✕Probably not a fit
Patients who are pregnant or deemed inappropriate for the study by the investigator will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of a deep neural network (DNN) in identifying mediastinal and hilar lymph nodes during endobronchial ultrasound (EBUS) procedures. It is a multi-center prospective feasibility study that trains the DNN on annotated ultrasound images to improve the segmentation of lymph nodes and blood vessels. The study consists of two parts: the first assesses the DNN's performance on static EBUS images, while the second evaluates its real-time application during EBUS procedures.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate and efficient evaluations of lung cancer, improving patient outcomes.
How similar studies have gone: While the use of artificial intelligence in medical imaging is a growing field, this specific application in EBUS is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subjects referred to thoracic department in any of the participating hospitals with undiagnosed enlarged mediastinal and hilar lymph nodes. * Subjects have to be ≥ 18 years of age Exclusion Criteria: * Pregnancy * Any patient that the Investigator feels is not appropriate for this study for any reason.
Where it's running
-
Department of Pulmonology, Levanger Hospital, North Trøndelag Hospital Trust
Levanger, Norway Recruiting -
Department of Thoracic Medicine, St Olavs Hospital
Trondheim, Norway Recruiting
Study contacts
- Study coordinator: Øyvind Ervik, MD
- Email: oyvind.ervik@ntnu.no
- Phone: +4791634595
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
ePRO in advanced lung cancer: emotional distress, brain metastasis, and symptom burden
This study tests how patients with advanced lung cancer—some with brain metastases—report emotional distress and symptoms over time using electronic questionnaires.
-
Urine VOC Test to Detect Lung Cancer in Never Smokers
A urine test that looks for volatile compounds is tested to see if it can help detect lung cancer in adults who have never smoked.
-
SI-B036 safety test in advanced and metastatic solid tumors
This early-phase study checks whether SI-B036 is safe and tolerable in adults with advanced or metastatic solid cancers who have had prior therapy.
-
Guaraná Supplement for Cancer-Related Fatigue in People Undergoing Treatment
This study tests whether taking guaraná capsules helps reduce cancer-related fatigue and improve quality of life in adults with breast, lung, colorectal, or gastric cancer who are actively receiving treatment.
-
ENPP1/cGAS and FAP in Solid Tumors in Vietnamese Patients
This Vietnam-based study will test ENPP1, cGAS, and FAP expression in archived tumor samples from Vietnamese adults with solid cancers using immunohistochemistry.
-
Olive oil before lung cancer surgery to see if it lowers chylothorax
This study tests whether drinking 40 mL of extra-virgin olive oil a few hours before lung cancer surgery can reduce chylothorax after tumor removal.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.