Using amino acids to improve recovery in critically ill pregnant women after surgery
the Value of Early Post-operative Elemental Amino Acids in Critically Ill Obstetrics, and Its Contribution to the Concept of ERAS
This study is testing if giving amino acids right after surgery can help critically ill pregnant women recover better after cesarean sections.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 16 Years to 50 Years |
| Sex | Female |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, القاهرة) |
| Trial ID | NCT06164301 on ClinicalTrials.gov |
What this trial studies
This trial evaluates the impact of early postoperative elemental amino acid supplementation on the recovery of critically ill women who have undergone cesarean sections. Patients will be closely monitored in the obstetrics ICU, where their nutritional status and clinical outcomes will be assessed. The study aims to determine if providing amino acids in the first two days post-surgery can enhance protein intake, gut function, and overall recovery quality. Participants will be randomly assigned to receive either the amino acid treatment or standard care.
Who should consider this trial
Good fit: Ideal candidates are critically ill female patients who have undergone cesarean sections and require ICU admission.
Not a fit: Patients with severe coagulopathy, decompensated heart failure, or significant metabolic disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve recovery times and outcomes for critically ill postpartum women.
How similar studies have performed: While this specific approach is novel, similar studies on nutritional interventions in critically ill patients have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Critically ill Female patients with cesarean section with or without hysterectomy that requires ICU admission pre or postoperative Exclusion Criteria: * Decompensated heart failure, * Known allergy * Tryptophan intolerance * known inborn errors of metabolism of proteins as alkaptonuria * severe hepatic dysfunction (failure) * severe renal dysfunction (failure) * severe coagulopathy or DIC * circulatory shock or hemodynamic instability * Lactose intolerance * G6PD deficiency * Uncontrolled diabetic condition.
Where this trial is running
Cairo, القاهرة
- Ain shams university — Cairo, القاهرة, Egypt (Recruiting)
Study contacts
- Principal investigator: wessam selima, MD — assistant professor (lecturer)- Ain shams university
- Study coordinator: wessam selima, MD
- Email: w.z.selima@med.asu.edu.eg
- Phone: +201001958858
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.