Clinical trial Recruiting at 3 sites Interventional Ages 18 and up

Using air purifiers to help heart failure patients

Official title: Effectiveness of Indoor Air Purifiers on Heart Failure Outcomes

Run by NYU Langone Health · NCT05230784 · Data updated 2026-11-12

This study tests if using portable air purifiers can help heart failure patients in India breathe better and improve their heart function by reducing harmful air pollution.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment255 (estimated)
SponsorNYU Langone Health
Academic / other
Locations3 sites (Thiruvananthapuram, Kerala and 2 other locations)
StatusRecruiting
StartedMarch 6, 2024
Main results expectedFebruary 29, 2028
Study endsApril 30, 2028
Registry record updatedJanuary 29, 2026
Trial IDNCT05230784 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older diagnosed with heart failure with reduced ejection fraction of 40% or less within the last six months.

Probably not a fit

Patients who are listed for a cardiac transplant, have severe pulmonary disease, or are unable to ambulate may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial investigates the impact of portable air filters on indoor air quality and the functional capacity of heart failure patients with reduced ejection fraction in India. It aims to demonstrate the efficacy, feasibility, and effectiveness of these air purifiers in reducing PM2.5 levels, which are known to contribute to cardiovascular issues. The study will compare the effects of an active air purifier against a placebo filter among eligible participants. The findings could provide insights into innovative strategies for improving both environmental and cardiovascular health.

Why it matters

Potential benefit: If successful, this study could lead to improved health outcomes for heart failure patients by enhancing their functional capacity through better air quality.

How similar studies have gone: While the approach of using air purifiers for heart failure patients is innovative, similar studies have shown potential benefits of improving air quality on cardiovascular health.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults ≥ 18 years of age diagnosed with HF with a reduced ejection fraction of ≤ 40% within the last six months in NYHA class II-IV.

Exclusion Criteria:

* listed for a cardiac transplant
* history of CRT device implantation in last 3 months
* on oxygen therapy
* with severe pulmonary disease
* participants unable to ambulate

Where it's running

  • Centre for Chronic Disease Control (CCDC)
    Thiruvananthapuram, Kerala, India
    Recruiting
  • All India Institute of Medical Sciences (AIIMS)
    Delhi, Punjab, India
    Recruiting
  • Public Health Foundation of India (PHFI)
    Ludhiana, Punjab, India
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.