Using air purifiers to help heart failure patients
Official title: Effectiveness of Indoor Air Purifiers on Heart Failure Outcomes
Run by NYU Langone Health · NCT05230784 · Data updated 2026-11-12
This study tests if using portable air purifiers can help heart failure patients in India breathe better and improve their heart function by reducing harmful air pollution.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 255 (estimated) |
| Sponsor | NYU Langone Health Academic / other |
| Locations | 3 sites (Thiruvananthapuram, Kerala and 2 other locations) |
| Status | Recruiting |
| Started | March 6, 2024 |
| Main results expected | February 29, 2028 |
| Study ends | April 30, 2028 |
| Registry record updated | January 29, 2026 |
| Trial ID | NCT05230784 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older diagnosed with heart failure with reduced ejection fraction of 40% or less within the last six months.
✕Probably not a fit
Patients who are listed for a cardiac transplant, have severe pulmonary disease, or are unable to ambulate may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This trial investigates the impact of portable air filters on indoor air quality and the functional capacity of heart failure patients with reduced ejection fraction in India. It aims to demonstrate the efficacy, feasibility, and effectiveness of these air purifiers in reducing PM2.5 levels, which are known to contribute to cardiovascular issues. The study will compare the effects of an active air purifier against a placebo filter among eligible participants. The findings could provide insights into innovative strategies for improving both environmental and cardiovascular health.
Why it matters
Potential benefit: If successful, this study could lead to improved health outcomes for heart failure patients by enhancing their functional capacity through better air quality.
How similar studies have gone: While the approach of using air purifiers for heart failure patients is innovative, similar studies have shown potential benefits of improving air quality on cardiovascular health.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults ≥ 18 years of age diagnosed with HF with a reduced ejection fraction of ≤ 40% within the last six months in NYHA class II-IV. Exclusion Criteria: * listed for a cardiac transplant * history of CRT device implantation in last 3 months * on oxygen therapy * with severe pulmonary disease * participants unable to ambulate
Where it's running
-
Centre for Chronic Disease Control (CCDC)
Thiruvananthapuram, Kerala, India Recruiting -
All India Institute of Medical Sciences (AIIMS)
Delhi, Punjab, India Recruiting -
Public Health Foundation of India (PHFI)
Ludhiana, Punjab, India Recruiting
Study contacts
- Principal investigator: Rajesh Vedanthan, MD, MPH — NYU Langone Health
- Study coordinator: Rajesh Vedanthan, MD, MPH
- Email: Rajesh.vedanthan@nyulangone.org
- Phone: 646-501-3890
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.