Using AI to improve IVF and ART outcomes
Official title: The Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes
Run by Weill Medical College of Cornell University · NCT04255615 · Data updated 2026-11-12
This study is testing whether using artificial intelligence can help doctors better predict the success of IVF treatments by analyzing patient data and ultrasound images.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 89 Years |
| Sex | All |
| Enrollment | 4000 (estimated) |
| Sponsor | Weill Medical College of Cornell University Academic / other |
| Locations | 1 site (New York, New York) |
| Status | Recruiting |
| Started | February 12, 2020 |
| Main results expected | January 31, 2029 |
| Study ends | September 30, 2029 |
| Registry record updated | December 24, 2025 |
| Trial ID | NCT04255615 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals undergoing ovarian stimulation for IVF or assisted reproductive techniques, along with their healthy male partners.
✕Probably not a fit
Patients who are not undergoing ART cycles or those without male partners may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to utilize artificial intelligence to analyze clinical data and predict the outcomes of assisted reproductive techniques, specifically in vitro fertilization (IVF). By employing machine learning techniques, the study will assess baseline ovarian reserve through 3D transvaginal ultrasound imaging to objectively identify antral follicle counts. The goal is to develop an automated tool that reduces physician bias and enhances the accuracy of clinical assessments. Data will be collected from participants undergoing ovarian stimulation, including medical history and treatment outcomes.
Why it matters
Potential benefit: If successful, this approach could lead to improved IVF success rates and more personalized treatment plans for patients experiencing infertility.
How similar studies have gone: Other studies have shown promise in using AI for clinical assessments, suggesting potential for success in this novel application.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients undergoing ovarian stimulation (including OI and IVF cycles) * Treatment for fresh embryo transfer and cryopreservation of oocytes or embryos upfront * Healthy male partners of the female subjects who agree to be part of the study. Exclusion Criteria: * None
Where it's running
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Weill Cornell Medicine
New York, New York, United States Recruiting
Study contacts
- Principal investigator: Nikica Zaninovic, PHD — Weill Medical College of Cornell University
- Study coordinator: Nikica Zaninovic, PhD
- Email: nizanin@med.cornell.edu
- Phone: 646-962-2764
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Standardizing embryo transfer steps for frozen embryo transfers
This trial tests whether using specialized transfer devices to keep embryos warm and deliver them with precise, controlled motion can increase pregnancy success for people having frozen embryo transfer after IVF/ICSI.
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Levothyroxine for women with mild (subclinical) hypothyroidism having IVF/ICSI and frozen embryo transfer
This project will try giving low‑dose levothyroxine to women with subclinical hypothyroidism undergoing IVF/ICSI with frozen embryo transfer to see if it improves pregnancy outcomes.
-
AI-assisted embryo selection on day 5 in IVF for infertility
This trial tests whether an AI-based embryo selection tool can help pick the best embryo for transfer on day 5 in IVF/ICSI to improve pregnancy chances for people with infertility.
-
Preserving sperm quality with aging through cryopreservation
This study tests whether freezing and thawing sperm can help keep younger-like DNA and molecular traits in men as they age.
-
Unstimulated Egg Retrieval with CAPA-IVM and Euploid Embryo Transfer
This study tests whether eggs can be collected without ovarian stimulation, matured in the lab, and used to create a single euploid embryo for transfer in infertility patients.
-
Ultra-Long GnRH-a Pretreatment Before Frozen Embryo Transfer for Deep Infiltrating Endometriosis
In people under 40 with deep infiltrating endometriosis and infertility, the study tests whether two injections of a GnRH agonist before hormone support improve pregnancy outcomes in their first frozen-thawed embryo transfer.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.