Using advanced microscopy to study brain tissue and improve treatment for brain diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research aims to create a comprehensive database of various brain tissues to validate the use of human brain tissue models and human-induced pluripotent stem cells (hiPSCs)-derived organoid models. It focuses on brain diseases, particularly brain tumors, where obtaining functional brain tissue samples is challenging. The study will utilize an electrophysiological system and a multiphoton microscope to gather detailed information about brain diseases before surgical interventions. This approach seeks to enhance the accuracy of surgical resection strategies and improve patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1\. Patients older than the age of 18 with diagnosis of brain disease (both newly-diagnosed or recurrent) who are suitable and willing to receive resection surgery.

Exclusion Criteria:

1. Patients who cannot give consent to participate in the study.
2. The tumor samples failed to give a conclusive pathological diagnosis by standard pathological workflow.
3. Patients who only receives biopsy surgery rather than resection surgery.
4. Significant post-irradiation effect or radiation necrosis reported in the pathological examination.

Where it's running

• Department of Surgery, National Taiwan University Hospital and College of Medicine, National Taiwan University
  Taipei, Taiwan Recruiting

Study contacts

• Study coordinator: Kuo-Chuan Wang
• Email: wang081466@yahoo.com.tw
• Phone: +886-23123456

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.