Using advanced imaging to analyze skin health and diseases
Harmonics-based in Vivo Optical Virtual Biopsy
This study is testing a new imaging technique to see if it can help doctors better understand skin health and diseases like skin cancer and aging.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 500 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT01980264 on ClinicalTrials.gov |
What this trial studies
This research utilizes harmonic-based in vivo optical virtual biopsy to study the molecular and structural characteristics of human skin. By employing a Cr:forsterite laser and nonlinear optical microscopy, the study aims to capture detailed images of skin tissue for various purposes, including assessing melanin distribution, diagnosing skin cancers, analyzing skin aging, and examining microvascular changes in diabetic patients. The goal is to establish a comprehensive image database that can aid in early diagnosis and therapeutic analysis in dermatology.
Who should consider this trial
Good fit: Ideal candidates include healthy individuals of various skin types and ages, as well as patients with suspected skin cancers or diabetes.
Not a fit: Patients with infectious diseases or skin infections that cause ulceration may not benefit from this study.
Why it matters
Potential benefit: If successful, this technology could enable earlier and more accurate diagnosis of skin cancers and improve understanding of skin aging and diabetes-related skin conditions.
How similar studies have performed: Other studies utilizing advanced imaging techniques have shown promise in improving skin cancer diagnosis and understanding skin conditions, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. healthy volunteers of different skin colors and different ages 2. patients with suspected melanoma 3. patients with suspected basal cell carcinoma or squamous cell carcinoma 4. patients with diabetes mellitus Exclusion Criteria: 1. volunteers have infectious disease 2. volunteers' skin have been infected with ulceration
Where this trial is running
Taipei
- Department of Dermatology, National Taiwan University Hospital and College of Medicine, National Taiwan University — Taipei, Taiwan (Recruiting)
Study contacts
- Principal investigator: Yi-Hua Liao, Doctoral — National Taiwan University Hospital
- Study coordinator: Yi-Hua Liao, Doctoral
- Email: yihualiao@ntu.edu.tw
- Phone: (02)23123456
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.