Using advanced imaging technology for early-stage breast cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of the EndoScell Scanner, a novel intraoperative cellular probing technology, for detecting sentinel lymph nodes during breast cancer surgery. The technology utilizes real-time fluorescence microscopy to provide ultra-high-resolution images, allowing for rapid and accurate assessment of lymph node pathology. By improving the detection process, the study aims to enhance surgical outcomes and inform subsequent treatment strategies for patients undergoing sentinel lymph node biopsy. The trial is particularly relevant given the rising incidence of breast cancer in China and the increasing demand for breast-conserving surgical options.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years and older (inclusive)
* Female
* Preoperative pathology confirmed invasive breast carcinoma or ductal carcinoma in situ
* Scheduled for sentinel lymph node biopsy
* Capable of and willing to provide informed consent

Exclusion Criteria:

* Patients with a confirmed allergy to methylene blue or sodium citrate tracers
* Pregnant or lactating women
* Patients unwilling to participate in the clinical study

Where it's running

• Fudan University Shanghai Cancer Center
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Jiajian Chen, Doctor
• Email: elwin1020@163.com
• Phone: +8618017317219

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using indocyanine green to find sentinel lymph nodes during mastectomy

  This pilot will test whether injecting indocyanine green and using fluorescence during mastectomy can find sentinel lymph nodes in women with clinically node-negative invasive breast cancer.

  Recruiting at 2 sites St. Antonius Hospital · Zwolle, Overijssel and 1 other locations · NCT07362485

• Using indocyanine green to identify sentinel lymph nodes during breast cancer surgery

  This project tests whether indocyanine green dye and a fluorescence camera can be used instead of the radioactive tracer to find sentinel lymph nodes in adults having breast cancer surgery who are clinically node-negative.

  Recruiting at 7 sites St. Antonius Hospital · Alkmaar and 6 other locations · NCT07146295

• New imaging technology for identifying breast cancer and lymph node status

  This study is testing a new imaging technology to help doctors better identify breast cancer and check lymph nodes during surgery for patients with breast cancer.

  Recruiting Yunnan Cancer Hospital · Kunming, Yunnan · NCT06713161

• Tailoring axillary surgery for breast cancer patients

  This study is testing if some early breast cancer patients can skip certain surgeries to remove lymph nodes, which might help them avoid unnecessary complications and costs.

  Recruiting KK Women's and Children's Hospital · Singapore · NCT06259513

• Using a low dose of Magtrace to locate lymph nodes in breast cancer patients

  This study is testing if a low dose of a new tracer can help find lymph nodes in breast cancer patients as well as the traditional methods do.

  Recruiting Phase 2 Vastra Gotaland Region · Gothenburg · NCT06169072

• Avoiding sentinel lymph node biopsy in early breast cancer patients

  This study is testing whether women with early breast cancer can safely skip a specific lymph node surgery to see if it helps them recover better and have less swelling in their arms.

  Recruiting The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT05935150

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.