Using advanced genetic testing to improve diagnosis of bile duct tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance the diagnostic accuracy for biliary tract tumors by developing a specific next-generation sequencing (NGS) panel tailored for dysplasia and cholangiocarcinoma (CCA). Patients undergoing biliary tract resection will have their tissue samples analyzed to identify genetic markers that could improve sensitivity compared to traditional histological methods. The study will enroll 50 patients over a period of 36 months, collecting clinical and instrumental data to support the analysis. The samples will be processed at the Pathological Anatomy department of the IRCCS Azienda Ospedaliero-Universitaria di Bologna.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Availability of enough tissue for histological and NGS analysis (at least 20 ng DNA).
* Age greater than/equal to 18 years.

Exclusion Criteria:

* None

Where it's running

• IRCCS Azienda Ospedaliero-Universitaria di Bologna
  Bologna, Italy Recruiting

Study contacts

• Principal investigator: Francesco Vasuri, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
• Study coordinator: Francecso Vasuri, MD
• Email: francesco.vasuri2@unibo.it
• Phone: 0512143761

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.