Using a VR app to improve cognitive skills in patients with mild cognitive impairment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of a telerehabilitation program that incorporates a virtual reality (VR) app aimed at enhancing cognitive performance and social skills in patients with Subjective Cognitive Decline (SCD) and Mild Cognitive Impairment (MCI). Participants will undergo initial assessments including neurological exams and neuropsychological tests, followed by a 6-week intervention where one group uses the VR app while another group engages in traditional cognitive rehabilitation. The study will measure changes in cognitive functions, social skills, brain activity, eye movements, and gait patterns to determine the efficacy of the VR approach compared to conventional methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects diagnosed with MCI (AD and PD) according to the criteria of the National Institute on Aging-Alzheimer's Association (NIA-AA, Albert et al., 2011)
* Subjects diagnosed with SCD according to diagnostic criteria proposed in research settings (Molinuevo et al., 2017)
* All enrolled subjects must be aged between 40 and 80 years and have at least 5 years of education

Exclusion Criteria:

* Presence of psychiatric disorders (major depression, psychosis, anxiety disorders)
* Presence of severe dementia
* History of cerebral ischemia
* Contraindications to brain MRI: pregnant women, pacemakers, non-latest-generation metal joint prostheses, electrodes, neurostimulators, or prostheses that may interfere with magnetic fields, unless there is a written statement of suitability from the specialist who performed the intervention

Where it's running

• IRCCS Centro Neurolesi Bonino Pulejo
  Messina, Italy, Italy Recruiting

Study contacts

• Study coordinator: Maria Grazia Maggio, PhD, PsyD
• Email: mariagrazia.maggio@irccsme.it
• Phone: +39 090 62128250

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.