Using a special probe to improve cancer surgery outcomes
Using a Diffuse Reflectance Spectroscopy Probe In-vivo to Identify Tumour and Non-tumour Tissue in the Gastrointestinal Tract to Aid Margin Assessment
NA · Imperial College London · NCT05830292
This study tests whether a special probe can help surgeons remove all of a tumor while saving healthy tissue during gastrointestinal cancer surgeries.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 99 Years |
| Sex | All |
| Sponsor | Imperial College London (other) |
| Locations | 1 site (London) |
| Trial ID | NCT05830292 on ClinicalTrials.gov |
What this trial studies
This study utilizes a diffuse reflectance spectroscopy (DRS) probe during gastrointestinal cancer surgeries to enhance the accuracy of tumor margin assessments. The probe illuminates tissue and collects reflected light to create detailed spectroscopic images, helping surgeons differentiate between normal and cancerous tissues in real-time. By tracking the probe's position, the research team aims to ensure complete tumor resection while preserving healthy tissue. The study is conducted in the operating theatre with participants undergoing elective GI cancer surgeries at Imperial College NHS Trust.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 undergoing elective primary surgeries for upper or lower gastrointestinal cancers.
Not a fit: Patients who are undergoing emergency surgeries, re-operations, or who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved surgical outcomes and reduced recurrence rates for patients with gastrointestinal cancer.
How similar studies have performed: Previous studies using similar spectroscopic techniques have shown promise in improving cancer diagnosis and surgical outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing primary upper GI cancer resection surgery * Patients undergoing primary lower GI (colorectal) cancer resection surgery * Patients \>18 years of age * Patients who consent to take part in the study Exclusion Criteria: * Patients who do not consent to the study or decline to participate * Patients who do not meet the inclusion criteria * Patients who lack capacity * Patients undergoing emergency lower or upper GI cancer surgery * Patients undergoing re-operation for cancer surgery * Pregnant women
Where this trial is running
London
- Imperial College NHS Trust — London, United Kingdom (RECRUITING)
Study contacts
- Study coordinator: Christopher Peters, PhD
- Email: christopher.peters@imperial.ac.uk
- Phone: 020 3312 6666
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gastrointestinal Cancer, cancer, artificial intelligence, diffuse reflectance spectroscopy, gastrointestinal