Using a prediction index to prevent low blood pressure during heart surgery
Hypotension Prediction Index for Prevention of Hypotension During Cardiac Surgery: A Randomized Controlled Trial
This study is testing if a new tool can help prevent low blood pressure during heart surgery for adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 110 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mackay Memorial Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT06137547 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of the hypotension prediction index (HPI) in preventing low blood pressure during cardiac surgery. It involves a randomized, single-blind design where adult patients scheduled for elective primary cardiac surgery will be assigned to either HPI-guided or standard hemodynamic management. The primary focus is on measuring the average time patients experience hypotension during surgery, while secondary outcomes include monitoring postoperative complications. The study aims to confirm the clinical benefits of HPI in a cardiac surgery setting.
Who should consider this trial
Good fit: Ideal candidates are adults undergoing elective primary coronary artery bypass grafting (CABG) or isolated valve surgery.
Not a fit: Patients with arrhythmias, intracardiac shunts, or those requiring urgent/emergent procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of hypotension and related complications during and after cardiac surgery.
How similar studies have performed: Previous studies have shown promising results for the hypotension prediction index in non-cardiac surgeries, but its application in cardiac surgery remains to be fully validated.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * adult * elective, primary, isolated coronary arterial bypass surgery (CABG) or isolated valve surgery * provide inform consent. Exclusion Criteria: * arrhythmia (e.g., atrial fibrillation, atrial flutter) * intracardiac shunts * preoperative inotropic usage * preoperative supportive devices usage (e.g., intra-aortic balloon pump, extracorporeal membrane oxygenation, left ventricular assist device, or right ventricular assist device) * receiving urgent or emergent procedures.
Where this trial is running
Taipei
- Mackay memorial hospital — Taipei, Taiwan (Recruiting)
Study contacts
- Study coordinator: Ying-Chun Lin, Master
- Email: elegant.beaver@gmail.com
- Phone: +886-02-25433535
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.