Using a prediction index to prevent low blood pressure during heart surgery
Official title: Hypotension Prediction Index for Prevention of Hypotension During Cardiac Surgery: A Randomized Controlled Trial
Run by Mackay Memorial Hospital · NCT06137547 · Data updated 2026-11-12
This study is testing if a new tool can help prevent low blood pressure during heart surgery for adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 110 (estimated) |
| Sponsor | Mackay Memorial Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | November 20, 2023 |
| Main results expected | July 31, 2027 |
| Study ends | August 31, 2027 |
| Registry record updated | May 8, 2025 |
| Trial ID | NCT06137547 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults undergoing elective primary coronary artery bypass grafting (CABG) or isolated valve surgery.
✕Probably not a fit
Patients with arrhythmias, intracardiac shunts, or those requiring urgent/emergent procedures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effectiveness of the hypotension prediction index (HPI) in preventing low blood pressure during cardiac surgery. It involves a randomized, single-blind design where adult patients scheduled for elective primary cardiac surgery will be assigned to either HPI-guided or standard hemodynamic management. The primary focus is on measuring the average time patients experience hypotension during surgery, while secondary outcomes include monitoring postoperative complications. The study aims to confirm the clinical benefits of HPI in a cardiac surgery setting.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of hypotension and related complications during and after cardiac surgery.
How similar studies have gone: Previous studies have shown promising results for the hypotension prediction index in non-cardiac surgeries, but its application in cardiac surgery remains to be fully validated.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * adult * elective, primary, isolated coronary arterial bypass surgery (CABG) or isolated valve surgery * provide inform consent. Exclusion Criteria: * arrhythmia (e.g., atrial fibrillation, atrial flutter) * intracardiac shunts * preoperative inotropic usage * preoperative supportive devices usage (e.g., intra-aortic balloon pump, extracorporeal membrane oxygenation, left ventricular assist device, or right ventricular assist device) * receiving urgent or emergent procedures.
Where it's running
-
Mackay memorial hospital
Taipei, Taiwan Recruiting
Study contacts
- Study coordinator: Ying-Chun Lin, Master
- Email: elegant.beaver@gmail.com
- Phone: +886-02-25433535
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Manual versus automated heart strain measurement during cardiac surgery
This test tries to see if fully automated strain analysis of transesophageal echocardiography can give reliable, fast measurements of left ventricular function for adults having cardiac surgery.
-
Slow Jogging for Breast Cancer Survivors
This study tests whether a 12-week slow jogging program helps sleep quality in women who have completed breast cancer treatment.
-
Probiotics to improve sperm count, motility, and morphology in men with low sperm quality
This study tests whether daily probiotic supplements can improve sperm count, motility, and morphology in men with unexplained low sperm quality.
-
Life after hospital for cardiogenic shock survivors
This project follows adults who survived cardiogenic shock after hospital discharge to see how they recover and what care they need.
-
Using Auricular Acupressure to Improve Sleep Quality in Nurses
This study tests if auricular acupressure can help nurses who struggle with sleep due to their busy schedules get better rest.
-
Multimedia childbirth prediction for first-time mothers and their partners
This project tests whether a multimedia program for first-time, low-risk mothers and their partners can reduce hospital visits, lower anxiety, and increase confidence near term.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.