Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using a prediction index to prevent low blood pressure during heart surgery

Official title: Hypotension Prediction Index for Prevention of Hypotension During Cardiac Surgery: A Randomized Controlled Trial

Run by Mackay Memorial Hospital · NCT06137547 · Data updated 2026-11-12

This study is testing if a new tool can help prevent low blood pressure during heart surgery for adults.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment110 (estimated)
SponsorMackay Memorial Hospital
Academic / other
Locations1 site (Taipei)
StatusRecruiting
StartedNovember 20, 2023
Main results expectedJuly 31, 2027
Study endsAugust 31, 2027
Registry record updatedMay 8, 2025
Trial IDNCT06137547 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults undergoing elective primary coronary artery bypass grafting (CABG) or isolated valve surgery.

Probably not a fit

Patients with arrhythmias, intracardiac shunts, or those requiring urgent/emergent procedures may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of the hypotension prediction index (HPI) in preventing low blood pressure during cardiac surgery. It involves a randomized, single-blind design where adult patients scheduled for elective primary cardiac surgery will be assigned to either HPI-guided or standard hemodynamic management. The primary focus is on measuring the average time patients experience hypotension during surgery, while secondary outcomes include monitoring postoperative complications. The study aims to confirm the clinical benefits of HPI in a cardiac surgery setting.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the incidence of hypotension and related complications during and after cardiac surgery.

How similar studies have gone: Previous studies have shown promising results for the hypotension prediction index in non-cardiac surgeries, but its application in cardiac surgery remains to be fully validated.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* adult
* elective, primary, isolated coronary arterial bypass surgery (CABG) or isolated valve surgery
* provide inform consent.

Exclusion Criteria:

* arrhythmia (e.g., atrial fibrillation, atrial flutter)
* intracardiac shunts
* preoperative inotropic usage
* preoperative supportive devices usage (e.g., intra-aortic balloon pump, extracorporeal membrane oxygenation, left ventricular assist device, or right ventricular assist device)
* receiving urgent or emergent procedures.

Where it's running

  • Mackay memorial hospital
    Taipei, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.