Using a new method to assess chest pain in emergency departments
Use of Determine Learning-based Cardiodynamicsgram (CDG) for Rapid and Precise Stratification of Chest Pain in Emergency Department
This study is testing a new method called cardiodynamicsgram to see if it can better identify heart problems in people with chest pain in the emergency department compared to the usual heart tests.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 8000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Qilu Hospital of Shandong University Academic / other |
| Locations | 1 site (Jinan, Shandong) |
| Trial ID | NCT06669884 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the effectiveness of a novel technique called cardiodynamicsgram (CDG) for the rapid and precise stratification of patients presenting with chest pain in the emergency department. The study focuses on individuals suspected of having acute coronary syndrome (ACS) and will analyze the accuracy of CDG in identifying myocardial ischemia compared to traditional electrocardiograms (ECGs). By leveraging determine-learning, the study seeks to improve the interpretation of ECG signals, which have remained largely unchanged for a century. The findings could enhance clinical decision-making and patient outcomes in emergency settings.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 years or older who present with symptoms of acute chest pain and are suspected of having acute coronary syndrome.
Not a fit: Patients diagnosed with ST-segment elevation myocardial infarction (STEMI) or those with severe hemodynamic instability will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and timely diagnoses of myocardial ischemia in patients with chest pain.
How similar studies have performed: While traditional ECG methods have been widely used, the CDG approach is novel and has not been extensively tested in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * aged 18 years or older * Those with suspected ACS who have symptoms of acute chest pain, visiting in the emergency department Exclusion Criteria: * Those who diagnosed with ST-segment elevation myocardial infarction (STEMI) * Those with hemodynamic instability (cardiogenic shock, cardiac arrest) * Those with malignant arrhythmias(ventricular tachycardia, ventricular fibrillation, third-degree atrioventricular block) * Those with aortic coarctation, or acute pulmonary embolism * Those who has an unanalysable ECG report due to loosened leads, unstable baseline, or signal interference, etc.
Where this trial is running
Jinan, Shandong
- Qilu Hospital of Shandong University — Jinan, Shandong, China (Recruiting)
Study contacts
- Principal investigator: Yuguo Chen, Professor — Qliu Hospital of Shandong University
- Study coordinator: Jiaojiao Pang, Doctor
- Email: jiaojiaopang@126.com
- Phone: 0086-0531-82165674
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.