Clinical trial Recruiting at 2 sites Interventional Ages 18 and up

Upper body high-intensity interval training for heart failure patients

Official title: The Effect of Upper Extremity Low-Volume High-Intensity Interval Training on Physical and Cognitive Functions in Heart Failure Patients

Run by Tarsus University · NCT06754475 · Data updated 2026-11-12

This study tests if a special type of exercise program for the upper body can help people with heart failure feel stronger and think better.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorTarsus University
Academic / other
Locations2 sites (Mersin, Mersin and 1 other locations)
StatusRecruiting
StartedNovember 1, 2024
Main results expectedNovember 1, 2026
Study endsDecember 1, 2026
Registry record updatedJanuary 3, 2025
Trial IDNCT06754475 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old with stable heart failure classified as New York Heart Association functional class I-II to III.

Probably not a fit

Patients with severe heart conditions or significant comorbidities that affect exercise capacity may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of low-volume high-intensity interval training (LV-HIIT) on physical and cognitive function in patients with heart failure with preserved ejection fraction (HFpEF). It is designed as a randomized controlled trial where patients will be divided into an intervention group receiving LV-HIIT and a control group receiving standard medical treatment. The intervention consists of structured exercise sessions on an arm ergometer over 8 weeks, focusing on improving exercise capacity and cognitive functions. Evaluations will include physical function assessments, muscle strength, fatigue, and mental health indicators before and after the intervention.

Why it matters

Potential benefit: If successful, this approach could enhance physical and cognitive functions in heart failure patients, improving their overall quality of life.

How similar studies have gone: Other studies have shown promising results with high-intensity interval training in heart failure populations, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical condition stable for ≥4 weeks.
* New York Heart Association functional classification I-II to III
* Over 18 years old

Exclusion Criteria:

History of CABG surgery

* Unstable angina pectoris
* Severe arrhythmia
* Acute pericarditis, endocarditis, myocarditis
* Severe left ventricular failure (EF \<40%)
* Acute pulmonary embolism
* History of syncope
* Dissecting aneurysm
* Thrombophlebitis
* Orthopedic disorders that may interfere with exercise
* Uncontrolled hypertension, severe pulmonary arterial hypertension
* Moderate-severe valve disease
* Decompensated Congestive Heart Failure
* Electrolyte abnormalities
* Hypertrophic Cardiomyopathy

Where it's running

  • Tarsus University, TARSUS, Mersin
    Mersin, Mersin, Turkey (Türkiye)
    Recruiting
  • Nurel Ertürk, TARSUS, Mersin
    Yenişehir, Mersin, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.