Upper body high-intensity interval training for heart failure patients

The Effect of Upper Extremity Low-Volume High-Intensity Interval Training on Physical and Cognitive Functions in Heart Failure Patients

Not applicable Interventional Tarsus University · NCT06754475

This study tests if a special type of exercise program for the upper body can help people with heart failure feel stronger and think better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorTarsus University Academic / other
Locations2 sites (Mersin, Mersin and 1 other locations)
Trial IDNCT06754475 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of low-volume high-intensity interval training (LV-HIIT) on physical and cognitive function in patients with heart failure with preserved ejection fraction (HFpEF). It is designed as a randomized controlled trial where patients will be divided into an intervention group receiving LV-HIIT and a control group receiving standard medical treatment. The intervention consists of structured exercise sessions on an arm ergometer over 8 weeks, focusing on improving exercise capacity and cognitive functions. Evaluations will include physical function assessments, muscle strength, fatigue, and mental health indicators before and after the intervention.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old with stable heart failure classified as New York Heart Association functional class I-II to III.

Not a fit: Patients with severe heart conditions or significant comorbidities that affect exercise capacity may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance physical and cognitive functions in heart failure patients, improving their overall quality of life.

How similar studies have performed: Other studies have shown promising results with high-intensity interval training in heart failure populations, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical condition stable for ≥4 weeks.
* New York Heart Association functional classification I-II to III
* Over 18 years old

Exclusion Criteria:

History of CABG surgery

* Unstable angina pectoris
* Severe arrhythmia
* Acute pericarditis, endocarditis, myocarditis
* Severe left ventricular failure (EF \<40%)
* Acute pulmonary embolism
* History of syncope
* Dissecting aneurysm
* Thrombophlebitis
* Orthopedic disorders that may interfere with exercise
* Uncontrolled hypertension, severe pulmonary arterial hypertension
* Moderate-severe valve disease
* Decompensated Congestive Heart Failure
* Electrolyte abnormalities
* Hypertrophic Cardiomyopathy

Where this trial is running

Mersin, Mersin and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions High Intensity Interval TrainingHeart FailureExerciseshigh intensity interval trainingupper extremityexercises capacity
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.