Clinical trial Recruiting at 1 site Interventional

Improving prevention of catheter-related bloodstream infections in ICUs

Official title: A Multicenter Clinical Translational Study of "ICU-NO CRBSI" Based on Improvement Science in China

Run by Fudan University · NCT06085690 · Data updated 2026-11-12

This study is testing a new approach to help hospitals in intensive care units prevent infections related to catheters by making sure doctors and nurses follow the best care practices.

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Quick facts

Study typeInterventional
SexAll
Enrollment8050 (estimated)
SponsorFudan University
Academic / other
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedSeptember 4, 2023
Main results expectedSeptember 30, 2025
Study endsDecember 31, 2025
Registry record updatedNovember 17, 2025
Trial IDNCT06085690 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are ICU patients who have been hospitalized for more than 48 hours and have a central venous catheter in place for over 24 hours.

Probably not a fit

Patients who are pregnant, have a history of CRBSI infection, or have central venous catheters placed in other hospitals may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter clinical trial aims to implement and evaluate a continuous quality improvement project called 'ICU-NO CRBSI' to prevent catheter-related bloodstream infections (CRBSI) in intensive care units. The study involves a cluster-randomized controlled design across 23 medical institutions, focusing on compliance with evidence-based practices for central venous catheter care. Participants will be monitored over several months to assess the effectiveness of the intervention and the necessary support for quality improvement. The study will analyze the incidence of CRBSI and adherence to prevention protocols among healthcare providers.

Why it matters

Potential benefit: If successful, this study could significantly reduce the incidence of CRBSI in ICU patients, leading to better patient outcomes and lower healthcare costs.

How similar studies have gone: Other studies have shown success with similar evidence-based interventions aimed at reducing CRBSI, indicating a promising approach for this trial.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ICU stay over 48 hours
* CVC was placed for more than 24 hours

Exclusion Criteria:

* Pregnant patients
* Patients with a history of CRBSI infection
* Patients with central venous catheterization were brought in from other hospitals

Where it's running

  • ZhongShan Hospital Affilicated to Fudan University
    Shanghai, Shanghai Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.