Improving prevention of catheter-related bloodstream infections in ICUs
A Multicenter Clinical Translational Study of "ICU-NO CRBSI" Based on Improvement Science in China
This study is testing a new approach to help hospitals in intensive care units prevent infections related to catheters by making sure doctors and nurses follow the best care practices.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 8050 (estimated) |
| Sex | All |
| Sponsor | Fudan University Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Trial ID | NCT06085690 on ClinicalTrials.gov |
What this trial studies
This multicenter clinical trial aims to implement and evaluate a continuous quality improvement project called 'ICU-NO CRBSI' to prevent catheter-related bloodstream infections (CRBSI) in intensive care units. The study involves a cluster-randomized controlled design across 23 medical institutions, focusing on compliance with evidence-based practices for central venous catheter care. Participants will be monitored over several months to assess the effectiveness of the intervention and the necessary support for quality improvement. The study will analyze the incidence of CRBSI and adherence to prevention protocols among healthcare providers.
Who should consider this trial
Good fit: Ideal candidates for this study are ICU patients who have been hospitalized for more than 48 hours and have a central venous catheter in place for over 24 hours.
Not a fit: Patients who are pregnant, have a history of CRBSI infection, or have central venous catheters placed in other hospitals may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly reduce the incidence of CRBSI in ICU patients, leading to better patient outcomes and lower healthcare costs.
How similar studies have performed: Other studies have shown success with similar evidence-based interventions aimed at reducing CRBSI, indicating a promising approach for this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ICU stay over 48 hours * CVC was placed for more than 24 hours Exclusion Criteria: * Pregnant patients * Patients with a history of CRBSI infection * Patients with central venous catheterization were brought in from other hospitals
Where this trial is running
Shanghai, Shanghai Municipality
- ZhongShan Hospital Affilicated to Fudan University — Shanghai, Shanghai Municipality, China (Recruiting)
Study contacts
- Study coordinator: CHUNLEI Li
- Email: 21211170023@m.fudan.edu.cn
- Phone: 15800488689
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.