Understanding thyroid tumors and their treatment

Studies on Thyroid Nodules and Thyroid Cancer

Observational National Institutes of Health Clinical Center (CC) · NCT00001160

This study is trying to learn more about thyroid nodules and cancer by looking at how well current treatments work and testing new ways to diagnose and treat these conditions in patients.

Quick facts

Study typeObservational
Enrollment2500 (estimated)
Ages6 Months to 98 Years
SexAll
SponsorNational Institutes of Health Clinical Center (CC) NIH
Locations1 site (Bethesda, Maryland)
Trial IDNCT00001160 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients diagnosed with or suspected to have thyroid nodules or thyroid cancer. It aims to enhance the understanding of diagnostic and treatment methods for thyroid conditions by utilizing standard medical care alongside new techniques. Participants will undergo various diagnostic procedures, including imaging and biopsies, while blood and tissue samples will be collected for research purposes. The study will also evaluate the effectiveness of radioiodine therapy and the significance of serum thyroglobulin measurements in diagnosing tumor recurrence.

Who should consider this trial

Good fit: Ideal candidates include adults and children aged 6 months and older with known or suspected thyroid nodules or thyroid cancer.

Not a fit: Patients with serious underlying medical conditions that limit diagnostic testing or therapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic and treatment strategies for thyroid cancer, enhancing patient outcomes.

How similar studies have performed: Other studies have shown success in similar approaches to understanding thyroid cancer, but this study also incorporates novel techniques and methodologies.

Eligibility criteria

Show full inclusion / exclusion criteria
* INCLUSION CRITERIA:

In order to be eligible to participate in this study, an individual must meet all of the following criteria:

1. Male or female, adults or children \>= 6 months+.
2. Patients with known or suspected thyroid nodules and/or thyroid cancer.
3. At risk family members of patients who have a genetic susceptibility to developing thyroid cancer.

EXCLUSION CRITERIA:

An individual who meets any of the following criteria will be excluded from participation in this study:

1\. Serious underlying medical conditions that restrict diagnostic testing or therapy such as renal failure, congestive cardiac failure or active coexisting non-thyroid carcinoma requiring intervention before thyroid cancer is addressed.

Where this trial is running

Bethesda, Maryland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hurthle Cell Thyroid CancerTall Cell Variant Thyroid CancerFollicular Thyroid CancerThyroid CancerPapillary Thyroid CancerThyroid Fine Needle BiopsyRadioiodineDosimetry
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.