Understanding the natural history of stroke and its causes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather comprehensive data on patients with acute stroke or transient ischemic attacks (TIA) to better understand the natural history of these conditions. It will establish a registry of patients and collect clinical, laboratory, and radiological data to characterize the progression and outcomes of cerebrovascular diseases. The study will also explore relationships among various clinical variables and identify potential subjects for future research on stroke. Data will be collected from standard medical care procedures and additional research-focused assessments.

Why it matters

Who can join: the full rules

* INCLUSION CRITERIA:

In order to be eligible to participate in this study, an individual must meet all of the following criteria:

1. Aged \>=18
2. Presented to participating study site (ED, ICU, or inpatient unit) with or at risk of acute stroke, TIA, or other disturbances of cerebrovascular circulation

EXCLUSION CRITERIA:

An individual who meets any of the following criteria will be excluded from participation in this study:

1. Subjects with contraindication to MRI scanning will be excluded from any testing which involves the use of MRI. The contraindications include subjects with the following devices or conditions:

   * Central nervous system aneurysm clips
   * Implanted neural stimulator
   * Implanted cardiac pacemaker or defibrillator
   * Cochlear implant
   * Ocular foreign body (e.g. metal shavings)
   * Insulin pump
   * Metal shrapnel or bullet
   * Any implanted device that is incompatible with MRI

   Subjects with a condition precluding entry in the scanner (e.g. morbid obesity, Claustrophobia, etc.) will not be included in the MRI portion of this study.
2. Pregnancy

Where it's running

• Medstar Washington Hospital Center
  Washington D.C., District of Columbia, United States Recruiting
• Suburban Hospital - Johns Hopkins Medicine
  Bethesda, Maryland, United States Recruiting
• National Institutes of Health Clinical Center
  Bethesda, Maryland, United States Recruiting

Study contacts

• Principal investigator: Lawrence L Latour, Ph.D. — National Institute of Neurological Disorders and Stroke (NINDS)
• Study coordinator: Nicole L Peterkin
• Email: nicole.peterkin@nih.gov
• Phone: (301) 435-2395

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.