Understanding the causes of recurring venous thromboembolic disease
Official title: Prospective Cohort Study on the Determinants of Venous THromboembolic Recurrence. BREIZH-Cohorte
Run by University Hospital, Brest · NCT04297085 · Data updated 2026-11-12
This study is trying to find out why some people under 50 and cancer patients keep having blood clots and what might increase their chances of getting them again.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 3400 (estimated) |
| Sponsor | University Hospital, Brest Academic / other |
| Locations | 4 sites (Brest and 3 other locations) |
| Status | Recruiting |
| Started | May 28, 2020 |
| Main results expected | April 2050 |
| Study ends | April 2050 |
| Registry record updated | June 15, 2026 |
| Trial ID | NCT04297085 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals aged 18 and over with a diagnosis of thromboembolic venous disease, particularly those under 50 or any age with active cancer.
✕Probably not a fit
Patients who are foreign nationals or unable to communicate effectively may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to assess the incidence of recurrent thromboembolic venous disease and identify risk factors for recurrence in two specific groups: individuals under 50 years old and cancer patients. It focuses on the serious complications associated with deep vein thrombosis (DVT) and pulmonary embolism (PE), which can lead to significant mortality and long-term health issues. Participants will provide biological samples to aid in the research. The study is conducted at the University Hospital in Brest, France.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of thromboembolic venous disease, potentially reducing recurrence rates and associated complications.
How similar studies have gone: Other studies have shown success in understanding thromboembolic disease, but this specific cohort approach focusing on age and cancer status is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subject aged 18 or over, or a minor with the consent of the parents and the minor, presenting with a thromboembolic venous disease * 50 and under or any age if active cancer * Affiliated to social security * Accepting to participate in the study. Exclusion Criteria: * Inability to communicate (comprehension disorder). * Refusal to participate.
Where it's running
-
CHRU Brest
Brest, France Recruiting -
HIA Clermont Tonnerre Brest
Brest, France Recruiting -
CH Morlaix
Morlaix, France Recruiting -
CH de Cornouaille
Quimper, France Recruiting
Study contacts
- Principal investigator: Francis COUTURAUD, MD, PHD — EA3878 (GETBO), Brest University Hospital in France
- Study coordinator: Francis COUTURAUD, MD, PHD
- Email: francis.couturaud@chu-brest.fr
- Phone: 02 98 34 73 47
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.