Understanding the causes of inflammation in rare neuroimmunologic disorders
Collaboration on Neuroimmunology: Question, Understand, Educate, Restore - the Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders
This study is trying to find out what causes inflammation in people with rare neuroimmunologic disorders like Neuromyelitis Optica and Transverse Myelitis to help improve their treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 6 Years and up |
| Sex | All |
| Sponsor | University of Texas Southwestern Medical Center Academic / other |
| Locations | 1 site (Dallas, Texas) |
| Trial ID | NCT01623076 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify the biological causes of inflammation in patients with Neuromyelitis Optica, Transverse Myelitis, and related conditions. Participants will be treated according to their physician's decisions while providing data and biological samples for research. The study seeks to understand variability in patient responses to treatments and the biological events preceding disease relapses. By collecting and sharing this information, researchers hope to improve diagnostic and treatment strategies for these disorders.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 6 years or older diagnosed with Neuromyelitis Optica, Neuromyelitis Optica Spectrum Disorder, Transverse Myelitis, or Optic Neuritis.
Not a fit: Patients who are unable to maintain scheduled visits or have known HIV or hepatitis C infections may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better diagnostic and treatment options for patients with rare neuroimmunologic disorders.
How similar studies have performed: Other studies have shown success in understanding similar neuroimmunologic conditions, making this approach promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 6 years or greater * Male or Female * Patient or Parent (in the case of a minor) able to give informed consent * For patients 10 to 17, patient able to assent * Patient diagnosed with NMO, NMOSD, TM or ON Exclusion Criteria: * Unable to maintain scheduled visits * Patient has known HIV or hepatitis C infection
Where this trial is running
Dallas, Texas
- The University of Texas Southwestern Medical Center — Dallas, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Benjamin M Greenberg, MD — University of Texas Southwestern Medical Center
- Study coordinator: Taylor Hinojo
- Email: taylor.hinojo@utsouthwestern.edu
- Phone: 214-645-0555
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.