Understanding risk factors for Parkinson's disease through participant reports
Official title: Parkinson's Progression Markers Initiative Online Study (PPMI Online)
Run by Michael J. Fox Foundation for Parkinson's Research · NCT05065060 · Data updated 2026-11-12
This study is trying to find out what factors might increase the risk of getting Parkinson's disease by gathering information from people with and without the condition.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500000 (estimated) |
| Sponsor | Michael J. Fox Foundation for Parkinson's Research Academic / other |
| Locations | 1 site (San Francisco, California) |
| Status | Recruiting |
| Started | July 28, 2021 |
| Main results expected | December 2041 |
| Study ends | December 2041 |
| Registry record updated | September 8, 2026 |
| Trial ID | NCT05065060 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older, both those diagnosed with Parkinson's disease and those without a diagnosis.
✕Probably not a fit
Patients who are under 18 years old or those with other neurodegenerative disorders unrelated to Parkinson's disease may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Parkinson Progression Marker Initiative Online (PPMI Online) is an observational study that collects information from individuals with and without Parkinson's disease to identify risk and predictive factors associated with the condition. This initiative is part of a larger program aimed at discovering markers of disease progression, which can be utilized in clinical trials for therapies targeting the reduction of Parkinson's disability. Participants may be involved in various related protocols, enhancing the breadth of data collected for analysis.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and early identification of Parkinson's disease, potentially guiding preventive strategies and treatments.
How similar studies have gone: Other studies focusing on participant-reported outcomes in neurodegenerative diseases have shown promise, indicating that this approach could yield valuable insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Parkinson Disease (PD) Participants: * Male or female age 18 years or older. * Has received a diagnosis of Parkinson's disease Participants without PD: * Male or female age 18 years or older. * Has not received a diagnosis of Parkinson's disease
Where it's running
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UCSF Movement Disorders and Neuromodulation Center (MDNC)
San Francisco, California, United States Recruiting
Study contacts
- Principal investigator: Caroline Tanner, MD, PhD — University of California, San Francisco
- Study coordinator: University of California, San Francisco
- Email: info@ppmionline.org
- Phone: 877-525-7764
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.