Clinical trial Recruiting at 1 site Observational Ages 18 and up

Understanding risk factors for Parkinson's disease through participant reports

Official title: Parkinson's Progression Markers Initiative Online Study (PPMI Online)

Run by Michael J. Fox Foundation for Parkinson's Research · NCT05065060 · Data updated 2026-11-12

This study is trying to find out what factors might increase the risk of getting Parkinson's disease by gathering information from people with and without the condition.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment500000 (estimated)
SponsorMichael J. Fox Foundation for Parkinson's Research
Academic / other
Locations1 site (San Francisco, California)
StatusRecruiting
StartedJuly 28, 2021
Main results expectedDecember 2041
Study endsDecember 2041
Registry record updatedSeptember 8, 2026
Trial IDNCT05065060 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older, both those diagnosed with Parkinson's disease and those without a diagnosis.

Probably not a fit

Patients who are under 18 years old or those with other neurodegenerative disorders unrelated to Parkinson's disease may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Parkinson Progression Marker Initiative Online (PPMI Online) is an observational study that collects information from individuals with and without Parkinson's disease to identify risk and predictive factors associated with the condition. This initiative is part of a larger program aimed at discovering markers of disease progression, which can be utilized in clinical trials for therapies targeting the reduction of Parkinson's disability. Participants may be involved in various related protocols, enhancing the breadth of data collected for analysis.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and early identification of Parkinson's disease, potentially guiding preventive strategies and treatments.

How similar studies have gone: Other studies focusing on participant-reported outcomes in neurodegenerative diseases have shown promise, indicating that this approach could yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Parkinson Disease (PD) Participants:

  * Male or female age 18 years or older.
  * Has received a diagnosis of Parkinson's disease

Participants without PD:

* Male or female age 18 years or older.
* Has not received a diagnosis of Parkinson's disease

Where it's running

  • UCSF Movement Disorders and Neuromodulation Center (MDNC)
    San Francisco, California, United States
    Recruiting

Study contacts

  • Principal investigator: Caroline Tanner, MD, PhD — University of California, San Francisco
  • Study coordinator: University of California, San Francisco
  • Email: info@ppmionline.org
  • Phone: 877-525-7764

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.