Understanding recovery in children after cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore how children and their families recover from major cancer surgeries by utilizing smartwatches and questionnaires. Participants, including pediatric patients aged 3-18 and their primary caregivers, will wear smartwatches to collect digital biomarkers and complete surveys about their recovery. Additionally, blood samples will be taken during routine clinical blood draws to analyze proteins and metabolites associated with stress post-surgery. The study will track recovery patterns for up to one year following surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 3-25 years old at enrollment
* With solid tumors of the chest, abdomen, and extremities including neuroblastic tumors, sarcoma including soft tissue and bone, kidney tumors, liver tumors, ovarian tumors, lung and pleural-based tumors, and intestinal tumors

-OR-

* Guardian or primary caregiver of patient 3-25 years old with one of the aforementioned tumors.

Exclusion Criteria:

* Patients who are known to be pregnant or prisoners.

Where it's running

• Mayo Clinic
  Rochester, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Stephanie Polites, M.D., M.P.H. — Mayo Clinic
• Study coordinator: Mayo Clinic Pediatric Surgery Clinical Research Unit
• Email: DOSCRO2@mayo.edu
• Phone: 507-266-4467

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Hypofractionated radiation plus B7-H3 CAR T cells for children and young adults with relapsed sarcoma

  This will test whether short-course radiation given before B7-H3 CAR T-cell therapy is safe for children and young adults (≤21) with relapsed or refractory B7-H3–positive sarcomas.

  Recruiting Phase 1 St. Jude Children's Research Hospital · Memphis, Tennessee · NCT07222735

• Using modified T cells to treat certain solid tumors in children and young adults

  This study is testing a new treatment using modified T cells to see if it can help children and young adults with tough-to-treat solid tumors.

  Recruiting Phase 1 Stanford University · Palo Alto, California · NCT06500819

• Creating immune organoids to study pediatric cancers

  This study is trying to create mini immune systems from kids' tissues to see how they respond to different types of pediatric cancers.

  Recruiting at 2 sites Gustave Roussy, Cancer Campus, Grand Paris · Villejuif and 1 other locations · NCT05890781

• Using cabozantinib to prevent recurrence in high-risk pediatric solid tumors

  This study is testing if the drug cabozantinib can help prevent high-risk pediatric solid tumors, like neuroblastoma and sarcoma, from coming back after treatment.

  Recruiting at 6 sites Phase 2 Nationwide Children's Hospital · Birmingham, Alabama and 5 other locations · NCT05135975

• Collecting and storing samples from children and adults with common childhood cancers

  This study is collecting and storing samples from children and adults with common childhood cancers to help researchers learn more about these diseases and find better treatments.

  Recruiting National Institutes of Health Clinical Center (CC) · Washington D.C., District of Columbia and 4 other locations · NCT01109394

• FaceSay: a computer program to help kids recognize facial expressions and improve social interactions

  A computer-based FaceSay program is tested to see if it helps survivors of pediatric brain tumors who have social difficulties see facial expressions better and relate more comfortably with peers.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07923370

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.