Understanding recovery in children after cancer surgery
Digital Biomarker and Omics-Based Assessment of Surgical Resiliency in Children Undergoing Solid Tumor Resection: A Pilot Feasibility Study
This study looks at how children aged 3-18 and their families recover after cancer surgery by using smartwatches and surveys to gather information over a year.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 3 Years to 25 Years |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT06674811 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore how children and their families recover from major cancer surgeries by utilizing smartwatches and questionnaires. Participants, including pediatric patients aged 3-18 and their primary caregivers, will wear smartwatches to collect digital biomarkers and complete surveys about their recovery. Additionally, blood samples will be taken during routine clinical blood draws to analyze proteins and metabolites associated with stress post-surgery. The study will track recovery patterns for up to one year following surgery.
Who should consider this trial
Good fit: Ideal candidates include children aged 3-18 with solid tumors such as neuroblastoma, sarcoma, or kidney tumors, along with their primary caregivers.
Not a fit: Patients who are pregnant or prisoners will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for enhancing recovery and resilience in children undergoing cancer surgery.
How similar studies have performed: While the use of digital biomarkers in recovery monitoring is emerging, this specific approach is novel and has not been extensively tested in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 3-25 years old at enrollment * With solid tumors of the chest, abdomen, and extremities including neuroblastic tumors, sarcoma including soft tissue and bone, kidney tumors, liver tumors, ovarian tumors, lung and pleural-based tumors, and intestinal tumors -OR- * Guardian or primary caregiver of patient 3-25 years old with one of the aforementioned tumors. Exclusion Criteria: * Patients who are known to be pregnant or prisoners.
Where this trial is running
Rochester, Minnesota
- Mayo Clinic — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Stephanie Polites, M.D., M.P.H. — Mayo Clinic
- Study coordinator: Mayo Clinic Pediatric Surgery Clinical Research Unit
- Email: DOSCRO2@mayo.edu
- Phone: 507-266-4467
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.