Understanding Prognostic Factors in Esophageal Cancer Patients

Noninvasive Testing Procedures, Role of Biomarkers and Anticancer Treatments in Esophageal and Esophagogastric Cancer Survival and Quality of Life of Patients With Cancer of the Esophageopharyngeal and Oesophageophageophageal Junction

Observational Semmelweis University · NCT06713993

This study looks at patients with esophageal cancer to see which health factors might affect their recovery and overall well-being.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorSemmelweis University Academic / other
Locations1 site (Budapest)
Trial IDNCT06713993 on ClinicalTrials.gov

What this trial studies

This observational study aims to analyze patients with new-onset esophageal and esophagogastric junction tumors in Hungary to identify key prognostic parameters that may influence disease outcomes. Patients will undergo comprehensive assessments including physical, nutritional, and cardiovascular evaluations, along with non-invasive imaging techniques. The study will track changes in various health metrics over time and explore the relationship between these factors and patient morbidity and mortality. The goal is to uncover modifiable factors that could improve treatment outcomes.

Who should consider this trial

Good fit: Ideal candidates include adults over 18 years diagnosed with new-onset esophageal or esophagogastric junction tumors who are eligible for elective curative surgery.

Not a fit: Patients who have already received oncological treatment for their current disease or those unable to consent or cooperate may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved prognostic assessments and tailored interventions for patients with esophageal cancer.

How similar studies have performed: While similar studies have explored prognostic factors in cancer, this specific approach focusing on cardiovascular and nutritional parameters in esophageal cancer is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age over 18 years
* Diagnosis of new-onset esophageal, esophagogastric junction tumor
* Elective curative surgery (open/laparoscopic regardless of surgical technique)
* Patients who have not yet received oncological treatment for their present disease

Exclusion Criteria:

* Lack of consent
* Lack of cooperation
* Contraindications for some studies: If MR scan is contraindicated, cardiac MR scan is not performed

Where this trial is running

Budapest

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Esophageal CancerEsophageal cancerheart failuresarcopeniamalnutritionfrailtyheart functionEsophageal cancer surgery
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.