Understanding pain management after major surgery in Uganda
Perioperative Multimodal Analgesia Practices and Associated Acute Postoperative Pain in Patients Undergoing Major Surgery at Mulago National Referral Hospital
This study looks at how using different types of pain medications together can help adults manage pain better after major surgery in Uganda.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 449 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Makerere University Academic / other |
| Locations | 1 site (Kampala) |
| Trial ID | NCT06887153 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the use of multimodal analgesia for pain management in adult patients undergoing major surgery at Mulago National Referral Hospital. It will evaluate how frequently combinations of pain medications are used before, during, and after surgery, and whether these combinations lead to better pain control compared to single medications. Patient records will be analyzed, and participants will report their pain levels every six hours for 24 hours post-surgery. The study will focus on various surgical units including colorectal, upper gastrointestinal, spine, thoracic, and orthopedic surgeries.
Who should consider this trial
Good fit: Ideal candidates are adult patients aged 18 and older scheduled for elective major surgeries at the hospital.
Not a fit: Patients with reduced levels of consciousness, neurological deficits, or those classified as ASA > III may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve postoperative pain management strategies, leading to better patient outcomes.
How similar studies have performed: Previous studies have shown that multimodal analgesia can improve pain management outcomes, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients ≥18 years * Scheduled for elective orthopaedic, abdominal and thoracic surgeries * In the selected operating theatres during the study period Exclusion Criteria: * Reduced levels of consciousness or neurological deficits * ASA \>III
Where this trial is running
Kampala
- Mulago National Referral Hospital — Kampala, Uganda (Recruiting)
Study contacts
- Principal investigator: Emmanuel S. Aporu, MBChB — Makerere University
- Study coordinator: Emmanuel S. Aporu, MBChB
- Email: aporu1994@gmail.com
- Phone: +256 758662377
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.