Understanding Long-Acting HIV Prevention for Men Who Have Sex with Men

Implantable Long-Acting Pre-Exposure Prophylaxis for HIV Prevention With MSM: A Qualitative Study of Patient and Physician Perspectives

Observational University of Kentucky · NCT05420207

This study is trying to understand what men who have sex with men and their doctors in Texas think about a long-lasting HIV prevention method to help improve its use in healthcare.

Quick facts

Study typeObservational
Enrollment70 (estimated)
Ages18 Years to 45 Years
SexMale
SponsorUniversity of Kentucky Academic / other
Locations2 sites (Austin, Texas and 1 other locations)
Trial IDNCT05420207 on ClinicalTrials.gov

What this trial studies

This project aims to explore the perspectives of men who have sex with men (MSM) and primary care physicians in Texas regarding long-acting, implantable pre-exposure prophylaxis (LA-PrEP) for HIV prevention. By conducting interviews with both patients and physicians, the study seeks to identify barriers to the uptake of LA-PrEP and the training needs of healthcare providers. The findings will inform strategies to enhance the implementation of LA-PrEP in primary care settings, particularly focusing on the unique needs of MSM. The study does not involve any interventions but rather observational assessments to gather insights.

Who should consider this trial

Good fit: Ideal candidates for this study are HIV-negative men aged 18-45 who have male sexual partners and have visited a participating primary care practice in Texas within the last year.

Not a fit: Patients who do not speak English or Spanish, or who have cognitive impairments that prevent informed consent, will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved uptake of long-acting HIV prevention methods among MSM, ultimately reducing HIV transmission rates.

How similar studies have performed: While this approach is novel in its focus on LA-PrEP for MSM in primary care settings, similar studies have shown promise in understanding patient and physician perspectives on other implantable medications.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients must meet the following criteria:

  1. be a patient of one of the practices where physicians have agreed to participate or have been seen for a primary care visit in the past 12 months in the Dallas Austin, or San Antonio metro areas;
  2. be aged 18-45;
  3. be assigned male sex at birth and report having one or more male sexual partners in the past year; and
  4. be HIV negative.
* Physicians who are interested in participating must be a practicing primary care physician in the Dallas, San Antonio, or Austin metropolitan area and be willing to allow recruitment of patient participants from their practice.

Exclusion Criteria:

* Those individuals who speak a language other than English or Spanish will be excluded as well as those who present with a cognitive or other impairment that would prevent them for consenting to participate in the study.

Where this trial is running

Austin, Texas and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HIV PreventionPre Exposure ProphylaxisHIVMSMPrimary Care
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.