Understanding language changes in primary progressive aphasia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the neurological and linguistic decline in individuals diagnosed with primary progressive aphasia (PPA). Participants will undergo a series of assessments including neuropsychological testing, advanced imaging techniques like MRI and PET, and various cognitive experiments. The goal is to enhance awareness of PPA, educate the public about this disorder, and promote further research aimed at developing potential therapies. Participants may be invited to return every two years for follow-up assessments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of primary progressive aphasia
* Right-handed
* Native English speaker
* Visual acuity of 20/30 corrected
* Adequate hearing to follow conversation
* Safe for an MRI scan

Exclusion Criteria:

* Left-handedness
* Claustrophobia
* Presence of significant medical illness that initially or in the future could interfere with continued participation in the study

Where it's running

• Northwestern University
  Chicago, Illinois, United States Recruiting

Study contacts

• Principal investigator: Marsel Mesulam, MD — Northwestern University
• Study coordinator: Elizabeth A Haynes
• Email: PPA.Research@northwestern.edu
• Phone: 312-503-2398

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.