Understanding impulsivity and alcohol response in young adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the relationship between impulsivity and subjective response to alcohol in young adults, aiming to identify new targets for prevention and treatment of Alcohol Use Disorder (AUD). It addresses the urgent public health crisis of alcohol misuse among young adults, particularly as rates are rising in young women. The research will utilize ecological momentary assessment (EMA) over two years, involving lab assessments and daily evaluations to explore how these risk factors interact and contribute to alcohol misuse. The study will enroll 250 participants aged 21-25 who meet specific drinking criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 21-25 years old
* Report drinking to an estimated BAC \> .08% at least once in the past 30 days based on responses on the Timeline Followback (TLFB)
* Report drinking at least twice weekly in the past 30 days based on responses on the TLFB
* Fluency in English

Exclusion Criteria:

* Any serious medical problems (e.g., liver disease, cardiac abnormality, pancreatitis, diabetes, neurological problems, and gastrointestinal disorders)
* Body weight \< 110 or \> 210 pounds
* Axis I psychiatric disorders including substance use disorder other than mild or moderate alcohol or mild cannabis use disorder
* Current alcohol withdrawal or history of medically-assisted detoxification
* Two positive breath alcohol concentration (BrAC) readings (i.e., \> 0.00%) at an in-person screening appointment or experimental session
* Positive urine screen for illegal drugs other than cannabis
* Currently seeking or past-12-month history of inpatient or intensive treatment for addictive behaviors
* Current psychotropic medication use or receipt of a prescription for these medications in the past 30 days
* Psychosis or other psychiatric disability
* Pregnancy, nursing or lack of reliable birth control use for women
* Report smoking \> 5 cigarettes per day (to avoid acute nicotine effects or withdrawal during experimental sessions)

Where it's running

• Northeastern University
  Boston, Massachusetts, United States Recruiting
• Ohio State University
  Columbus, Ohio, United States Recruiting

Study contacts

• Principal investigator: Jessica Weafer, PhD — Ohio State University
• Study coordinator: Jessica Weafer, PhD
• Email: jessica.weafer@osumc.edu
• Phone: 614-257-2075

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.