Understanding how vaping affects blood vessels

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the impact of vaping on blood vessels, specifically focusing on early damage that may occur in lung vessels. It will compare current electronic cigarette users with healthy individuals who have never smoked or vaped. Participants will be adults aged 18-40, and the study will gather data on their vascular health to assess the effects of vaping. The findings could provide insights into the risks associated with vaping and inform public health strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Vapers Group:

1. Current electronic cigarette (EC) Puff Bar users defined as using EC either daily or occasionally in the past 30 days for at least 6 months, and with 5% nicotine concentration pods.
2. Adults aged 18-40 years

Healthy Group:

1. Healthy never smokers, never vapers
2. Adults aged 18-40 years

Exclusion Criteria:

1. Current or past smoking of tobacco cigarette (TC) or other tobacco/nicotine products (e.g., smokeless tobacco, Hookah) or marijuana will be excluded from the study.
2. Subjects with self-reported history of chronic health problems including asthma, chronic obstructive pulmonary disease (COPD), morbid obesity (BMI\>40 kg/m2), hypertension or diabetes
3. Pregnant or breastfeeding women

Where it's running

• University of Miami Health System
  Miami, Florida, United States Recruiting

Study contacts

• Principal investigator: Adam Wanner, MD — University of Miami
• Study coordinator: Adam Wanner, MD
• Email: awanner@med.miami.edu
• Phone: (305)243-2568

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• TUBSIS 2.0 — an online program to help adults reduce or quit smoking and vaping

  This program tests whether a free, anonymous, 4-week web-based course using mindfulness, self-compassion, and behavior-change techniques helps German-, English-, and Turkish-speaking adults who smoke or vape reduce or quit tobacco.

  Recruiting University of Zurich · Zurich · NCT07568483

• Social media support groups to help teens and young adults quit vaping

  This pilot tries a social-media group program called the Quit the Hit Toolkit to help adolescents and young adults who vape stop using nicotine.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07540780

• How synthetic nicotine and nicotine analogues behave in the body when vaped

  This study tests synthetic nicotine and related nicotine analogues in vapes to see how they move through and act in the body compared with regular nicotine.

  Recruiting Insel Gruppe AG, University Hospital Bern · Bern · NCT07348224

• Varenicline plus enhanced TMS to help adults quit smoking and vaping

  This study tests whether adding active enhanced accelerated transcranial magnetic stimulation (aTMS) to varenicline helps adults 18–65 quit nicotine use more effectively than varenicline with sham stimulation.

  Recruiting Phase 4 Massachusetts General Hospital · Boston, Massachusetts · NCT07145866

• Varenicline to help adults stop vaping

  This trial tests whether the smoking-cessation pill varenicline helps adults who vape daily quit e-cigarettes.

  Recruiting at 2 sites Phase 2 Yale University · New Haven, Connecticut and 1 other locations · NCT07040566

• Using tDCS (mild brain stimulation) to reduce vaping

  This project will try daily transcranial direct current stimulation (tDCS) to reduce cravings and vaping in adults who use nicotine e-cigarettes every day and are not planning to quit.

  Recruiting Centre for Addiction and Mental Health · Toronto, Ontario · NCT06885606

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.