Understanding how uninvestigated dyspepsia progresses to functional dyspepsia
The Clinical Course and Factors for the Progression of Uninvestigated Dyspepsia to Functional Dyspepsia
This study looks at how uninvestigated dyspepsia changes into functional dyspepsia in patients who have had symptoms for at least a month to better understand how to manage and treat it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 220 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Air Force Military Medical University, China Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Trial ID | NCT05823636 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the natural progression of uninvestigated dyspepsia to functional dyspepsia, focusing on patients who have experienced symptoms for at least one month. It seeks to identify factors that may influence this progression based on established diagnostic criteria. By analyzing the clinical course of these patients, the study hopes to provide insights into the management and treatment of dyspepsia. The research will be conducted at the Air Force Military Medical University in China.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who have experienced first-onset dyspepsia symptoms lasting between one to three months.
Not a fit: Patients with known gastrointestinal diseases or other conditions that could cause dyspeptic symptoms will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of dyspepsia progression, leading to better diagnosis and treatment strategies for patients.
How similar studies have performed: While there have been studies on dyspepsia, this specific focus on the progression from uninvestigated to functional dyspepsia is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged ≥ 18 years old who had first-onset dyspepsia with one or more symptoms of epigastric pain, epigastric burning, postprandial fullness, early satiation and that has lasted for more than 1 month to 3 months. Exclusion Criteria: 1. Patients with local or systemic diseases which may cause dyspeptic symptoms: Known active peptic ulcer, cholecystitis, gallstone, gastrointestinal obstruction, gastroparesis, and etc. 2. Known acute or chronic injury of liver or kidney 3. Obvious hematological abnormality, or endocrine and metabolic diseases 4. Known malignancy; Obvious cardiovascular or cerebrovascular diseases (such as coronary heart disease, arrhythmia, cerebral infarction and etc. 5. Other conditions which may be associated with dyspeptic symptoms (such as NSAIDs associated dyspepsia) 6. organ failure defined by Marshall standard or severe psychiatric illnesses 7. pregnancy or lactation 8. unable to provide consent
Where this trial is running
Xi'an, Shaanxi
- Air Force Military Medical University, China — Xi'an, Shaanxi, China (Recruiting)
Study contacts
- Study coordinator: Yanglin Pan, MD
- Email: yanglinpan@hotmail.com
- Phone: 13991811225
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.