Understanding how the brain navigates in real-world environments
Neural Correlates of Real World Spatial Navigation in Humans
This study is testing how brain stimulation can improve navigation and memory in people while they complete tasks in virtual and real-world environments.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 12 Years to 70 Years |
| Sex | All |
| Sponsor | University of California, Los Angeles Academic / other |
| Locations | 1 site (Los Angeles, California) |
| Trial ID | NCT04874220 on ClinicalTrials.gov |
What this trial studies
This study aims to explore the neural mechanisms involved in spatial navigation by utilizing deep brain recordings and stimulation during various memory tasks in virtual reality, augmented reality, and real-world settings. Participants will engage in tasks that assess cognitive and behavioral factors influencing deep brain activity. The research will focus on how memory-enhancing deep brain stimulation can affect navigation performance and memory recall.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 12 years or older who have undergone RNS system placement and can provide informed consent.
Not a fit: Patients who are unwilling to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatments for memory-related conditions by enhancing spatial navigation abilities.
How similar studies have performed: While the approach of using deep brain stimulation in navigation tasks is innovative, similar studies have shown promise in understanding brain functions related to memory and navigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 12 years of age or older and has undergone RNS system placement * Willing to provide informed consent and participate the study * Ability to read and write English fluently Exclusion Criteria: * Unwilling to provide informed consent
Where this trial is running
Los Angeles, California
- University of California Los Angeles — Los Angeles, California, United States (Recruiting)
Study contacts
- Principal investigator: Nanthia Suthana, PhD — University of California, Los Angeles
- Study coordinator: Sonja Hiller
- Email: shiller@mednet.ucla.edu
- Phone: 3107947517
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.