Understanding and enhancing memory during sleep

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to explore how memory processes and consolidation occur during sleep by directly recording brain activity from patients with epilepsy. The study will utilize auditory and electrical stimulation during sleep to investigate their effects on memory modulation. By analyzing single neurons and localized neuronal assemblies, researchers hope to uncover neural features associated with episodic experiences. The findings could provide insights into the mechanisms of memory consolidation and potential therapeutic approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All epilepsy patients between the ages of 18 and 65 who undergo depth electrode placement for clinical purposes
* Eligibility is determined by the epilepsy surgery team (based on neuropsychological testing and on psychiatric evaluation)
* Willing to provide informed consent and participate the study

Exclusion Criteria:

* Neurological or psychiatric issues, other than epilepsy, that would put the patient at risk
* Patient is younger than 18 or older than 65 years of age
* Unwilling to provide informed consent

Where it's running

• University of California Los Angeles
  Los Angeles, California, United States Recruiting

Study contacts

• Study coordinator: Andreina Hampton
• Email: amhampton@mednet.ucla.edu
• Phone: 3236105293

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.