Understanding how inactivity affects exercise benefits
Molecular Signature of Inactivity Induced Exercise Responsiveness
NA · Concordia University Wisconsin · NCT06301243
This study tests how being inactive affects the benefits of exercise for people who don’t currently work out, especially in relation to metabolic health.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 10 (estimated) |
| Ages | 18 Years to 35 Years |
| Sex | All |
| Sponsor | Concordia University Wisconsin (other) |
| Locations | 1 site (Mequon, Wisconsin) |
| Trial ID | NCT06301243 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of inactivity on the body's response to exercise, particularly focusing on metabolic diseases. It aims to explore how prolonged periods of low activity influence the effectiveness of aerobic exercise in improving fitness levels. By examining the molecular changes in muscle during and after exercise following periods of inactivity, the research seeks to provide insights into optimizing exercise recommendations. The study will involve participants who do not currently engage in structured exercise programs and are free from significant health issues.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals who are free from chronic illnesses and do not currently participate in structured exercise programs.
Not a fit: Patients with acute or chronic illnesses, orthopedic limitations, or those currently engaged in a structured exercise program may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could lead to more personalized exercise guidelines that enhance fitness outcomes for individuals with metabolic diseases.
How similar studies have performed: While there have been studies on inactivity and exercise, this specific focus on molecular responses in muscle during inactivity is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * free from acute or chronic illness (cardiac, pulmonary, liver, or kidney abnormalities, cancer, uncontrolled hypertension, insulin- or non-insulin dependent diabetes or other known metabolic disorders) * free from orthopedic limitations (including any artificial joints) no known lidocaine allergy * do not currently smoke or participate in other forms of tobacco use. * not currently in a structured exercise program
Where this trial is running
Mequon, Wisconsin
- Kevin J Gries — Mequon, Wisconsin, United States (RECRUITING)
Study contacts
- Study coordinator: Kevin J Gries, PhD
- Email: kevin.gries@cuw.edu
- Phone: 262-243-4293
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Metabolic Diseases, Aerobic Exercise